Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0087169
Disease: Withdrawal Symptoms
Withdrawal Symptoms
0.310 Therapeutic CTD_human Circadian alteration in neurobiology during protracted opiate withdrawal in rats. 20738730

2010

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0087169
Disease: Withdrawal Symptoms
Withdrawal Symptoms
0.310 Biomarker CTD_human Circadian alteration in neurobiology during protracted opiate withdrawal in rats. 20738730

2010

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0087169
Disease: Withdrawal Symptoms
Withdrawal Symptoms
0.310 Biomarker CTD_human Nicotine-induced antinociception, rewarding effects, and physical dependence are decreased in mice lacking the preproenkephalin gene. 15689546

2005

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0087169
Disease: Withdrawal Symptoms
Withdrawal Symptoms
0.310 Biomarker CTD_human Withdrawal symptom intensities demonstrated an inverse correlation with beta-endorphin and met-enkephalin levels, a direct linear correlation with amplitude height of the evoked potential, and blood pressure and heart rate changes. 15714323

2005

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0087169
Disease: Withdrawal Symptoms
Withdrawal Symptoms
0.310 Therapeutic CTD_human Withdrawal symptom intensities demonstrated an inverse correlation with beta-endorphin and met-enkephalin levels, a direct linear correlation with amplitude height of the evoked potential, and blood pressure and heart rate changes. 15714323

2005

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0087169
Disease: Withdrawal Symptoms
Withdrawal Symptoms
0.310 Therapeutic CTD_human Nicotine-induced antinociception, rewarding effects, and physical dependence are decreased in mice lacking the preproenkephalin gene. 15689546

2005

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0087169
Disease: Withdrawal Symptoms
Withdrawal Symptoms
0.310 Biomarker CTD_human In view of the appearance of mild withdrawal signs during this method of treatment, the observed increases in ACTH and cortisol levels probably reflect the inability of AES to suppress withdrawal symptoms induced by naloxone completely. 225122

1979

Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0087169
Disease: Withdrawal Symptoms
Withdrawal Symptoms
0.310 Therapeutic CTD_human In view of the appearance of mild withdrawal signs during this method of treatment, the observed increases in ACTH and cortisol levels probably reflect the inability of AES to suppress withdrawal symptoms induced by naloxone completely. 225122

1979