×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Endometrial Carcinoma
0.800
Biomarker
GENOMICS_ENGLAND
Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database.
24362816 2014
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Endometrial Carcinoma
0.800
Biomarker
CTD_human
Transcriptional profiling endometrial carcinomas microdissected from DES-treated mice identifies changes in gene expression associated with estrogenic tumor promotion.
16804899 2006
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Endometrial Carcinoma
0.800
Biomarker
CTD_human
Human endometrial carcinomas , as well as complex atypical hyperplasias (CAH), are estrogen related and frequently have mutations in the PTEN gene.
16402032 2006
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Endometrial Carcinoma
0.800
GeneticVariation
UNIPROT
MSH6 mutation carriers have later age of onset of both colorectal cancer (62 vs. 51 years) and endometrial cancer (58 vs. 48 years) and a larger proportion of endometrial cancer than MLH1 or MSH2 mutation carriers.14961575 2004
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Endometrial Carcinoma
0.800
Biomarker
CTD_human
In the present study, we have used an endometrial cancer cell line known to possess wild-type PTEN (HEC-1-A) and two mutated inactive PTEN protein cell lines (RL-95-2 and Ishikawa) to investigate importance of PI 3-K/PTEN/Akt survival pathway in endometrial cancers .
12888921 2003
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Endometrial Carcinoma
0.800
GeneticVariation
UNIPROT
Among MMR genes, germline MSH6 mutations are often observed in HNPCC-like families with an increased frequency of endometrial cancer .
11153917 2000
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Endometrial Carcinoma
0.800
Biomarker
CTD_human
Familial endometrial cancer in female carriers of MSH6 germline mutations.
10508506 1999
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Endometrial Carcinoma
0.800
Biomarker
CTD_human
PTEN1 is frequently mutated in primary endometrial carcinomas .9326929 1997
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Endometrial Carcinoma
0.800
Biomarker
GENOMICS_ENGLAND
Multiple hamartoma syndrome (Cowden's disease).
4635800 1972
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Endometrial Carcinoma
0.800
CausalMutation
CGI
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Endometrial Carcinoma
0.800
GeneticVariation
UNIPROT
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Endometrial Carcinoma
0.800
CausalMutation
CGI
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
Endometrial Carcinoma
0.800
Biomarker
GENOMICS_ENGLAND
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Endometrial Carcinoma
0.800
GenomicAlterations
CGI
×
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
Endometrial Carcinoma
0.700
Biomarker
CTD_human
Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase.
21936542 2011
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Endometrial Carcinoma
0.700
Biomarker
CTD_human
Mutations of the E-cadherin gene in human gynecologic cancers.
8075649 1994
×
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
Endometrial Carcinoma
0.700
CausalMutation
CGI
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Endometrial Carcinoma
0.700
CausalMutation
CGI
×
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
Endometrial Carcinoma
0.700
Biomarker
GENOMICS_ENGLAND
×
Entrez Id: 999
Gene Symbol: CDH1
CDH1
Endometrial Carcinoma
0.700
Biomarker
GENOMICS_ENGLAND
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Endometrial Carcinoma
0.700
Biomarker
GENOMICS_ENGLAND
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Endometrial Carcinoma
0.700
Biomarker
GENOMICS_ENGLAND
×
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
Endometrial Carcinoma
0.700
GenomicAlterations
CGI
×
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
Endometrial Carcinoma
0.700
CausalMutation
CGI
×
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
Endometrial Carcinoma
0.700
CausalMutation
CGI