Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human Sex differences in behavior and expression of CGRP-related genes in a rodent model of chronic migraine. 21521205

2011
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human Evidence of TRPV1 receptor and PKC signaling pathway in the antinociceptive effect of amyrin octanoate. 19646975

2009
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human Interaction of transient receptor potential vanilloid 4, integrin, and SRC tyrosine kinase in mechanical hyperalgesia. 18234883

2008
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human Impaired nociception and inflammatory pain sensation in mice lacking the prokineticin receptor PKR1: focus on interaction between PKR1 and the capsaicin receptor TRPV1 in pain behavior. 16793879

2006
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human Antinociceptive properties of mixture of alpha-amyrin and beta-amyrin triterpenes: evidence for participation of protein kinase C and protein kinase A pathways. 15626726

2005
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human Antinociceptive action of the extract and the flavonoid quercitrin isolated from Bauhinia microstachya leaves. 16259764

2005
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human Pharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesia. 10401557

1999
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human Oral antinociception and oedema inhibition produced by NPC 18884, a non-peptidic bradykinin B2 receptor antagonist. 10543429

1999
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human The involvement of K+ channels and Gi/o protein in the antinociceptive action of the gallic acid ethyl ester. 10499367

1999
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human The nonpeptide B2 receptor antagonist FR173657: inhibition of effects of bradykinin related to its role in nociception. 9720808

1998
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human Anti-hyperalgesic properties of the extract and of the main sesquiterpene polygodial isolated from the barks of Drymis winteri (Winteraceae). 9714424

1998
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance. 7881729

1995
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human BW373U86, a delta-opioid receptor agonist, reverses bradykinin-induced thermal allodynia in rhesus monkeys. 7493622

1995
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human Cytokine-mediated inflammatory hyperalgesia limited by interleukin-10. 7582491

1995
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human Kappa- and delta-opioids block sympathetically dependent hyperalgesia. 2010815

1991
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human Characterization of distinct phospholipases mediating bradykinin and noradrenaline hyperalgesia. 2128375

1990
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
CUI: C0751214
Disease: Hyperalgesia, Thermal
Hyperalgesia, Thermal 		0.300 Biomarker CTD_human Characterization of the arachidonic acid metabolites mediating bradykinin and noradrenaline hyperalgesia. 3061568

1988