|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Crystal structure of the WD40 domain dimer of LRRK2.
|
30635421 |
2019 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Rab29 activation of the Parkinson's disease-associated LRRK2 kinase.
|
29212815 |
2018 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
A pathway for Parkinson's Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain.
|
30398148 |
2018 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils.
|
29127255 |
2018 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in Parkinson's disease.
|
28720718 |
2017 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Structural interface between LRRK2 and 14-3-3 protein.
|
28202711 |
2017 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
Biomarker |
GENOMICS_ENGLAND |
Development of a human induced pluripotent stem cell (iPSC) line from a Parkinson's disease patient carrying the N551K variant in LRRK2 gene.
|
28395804 |
2017 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis.
|
29125462 |
2017 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
Biomarker |
GENOMICS_ENGLAND |
Reprogramming of a human induced pluripotent stem cell (iPSC) line from a Parkinson's disease patient with a R1628P variant in the LRRK2 gene.
|
28395802 |
2017 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.
|
26824392 |
2016 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Leucine-rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER-Golgi export.
|
25201882 |
2014 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk.
|
23395371 |
2013 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Systematic review and UK-based study of PARK2 (parkin), PINK1, PARK7 (DJ-1) and LRRK2 in early-onset Parkinson's disease.
|
22956510 |
2012 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Mutations in LRRK2 increase phosphorylation of peroxiredoxin 3 exacerbating oxidative stress-induced neuronal death.
|
21850687 |
2011 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Comprehensive analysis of LRRK2 in publicly available Parkinson's disease cases and neurologically normal controls.
|
18213618 |
2008 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease.
|
16333314 |
2006 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Parkinson's disease and LRRK2: frequency of a common mutation in U.S. movement disorder clinics.
|
16250030 |
2006 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
The familial Parkinsonism gene LRRK2 regulates neurite process morphology.
|
17114044 |
2006 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
LRRK2 mutations in Spanish patients with Parkinson disease: frequency, clinical features, and incomplete penetrance.
|
16533964 |
2006 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity.
|
16321986 |
2006 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
LRRK2 G2019S is a common mutation in Spanish patients with late-onset Parkinson's disease.
|
16298482 |
2006 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
A frequent LRRK2 gene mutation associated with autosomal dominant Parkinson's disease.
|
15680456 |
2005 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
Type and frequency of mutations in the LRRK2 gene in familial and sporadic Parkinson's disease*.
|
16251215 |
2005 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
LRRK2 R1441G in Spanish patients with Parkinson's disease.
|
15925109 |
2005 |
|
| Entrez Id: |
120892 |
| Gene Symbol: |
LRRK2 |
LRRK2
|
PARKINSON DISEASE 8 (disorder)
|
0.930 |
GeneticVariation |
UNIPROT |
An LRRK2 mutation as a cause for the parkinsonism in the original PARK8 family.
|
15880653 |
2005 |