Source: UNIPROT

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C1863051
Disease: ALZHEIMER DISEASE 2
ALZHEIMER DISEASE 2 		0.800 GeneticVariation UNIPROT ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion. 28111074

2017
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C1863051
Disease: ALZHEIMER DISEASE 2
ALZHEIMER DISEASE 2 		0.800 GeneticVariation UNIPROT Interaction of the N-terminal domain of apolipoprotein E4 with heparin. 11258893

2001
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C1863051
Disease: ALZHEIMER DISEASE 2
ALZHEIMER DISEASE 2 		0.800 GeneticVariation UNIPROT Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons. 11447277

2001
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C1863051
Disease: ALZHEIMER DISEASE 2
ALZHEIMER DISEASE 2 		0.800 GeneticVariation UNIPROT Virus-mediated transduction of apolipoprotein E (ApoE)-sendai develops lipoprotein glomerulopathy in ApoE-deficient mice. 10903326

2000
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C1863051
Disease: ALZHEIMER DISEASE 2
ALZHEIMER DISEASE 2 		0.800 GeneticVariation UNIPROT Apolipoprotein E-containing high density lipoprotein promotes neurite outgrowth and is a ligand for the low density lipoprotein receptor-related protein. 8939961

1996
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C1863051
Disease: ALZHEIMER DISEASE 2
ALZHEIMER DISEASE 2 		0.800 GeneticVariation UNIPROT Human apolipoprotein E. Role of arginine 61 in mediating the lipoprotein preferences of the E3 and E4 isoforms. 8071364

1994
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C1863051
Disease: ALZHEIMER DISEASE 2
ALZHEIMER DISEASE 2 		0.800 GeneticVariation UNIPROT Isoform-specific interactions of apolipoprotein E with microtubule-associated protein tau: implications for Alzheimer disease. 7972031

1994
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C1863051
Disease: ALZHEIMER DISEASE 2
ALZHEIMER DISEASE 2 		0.800 GeneticVariation UNIPROT Isoform-specific interactions of apolipoprotein E with the microtubule-associated protein MAP2c: implications for Alzheimer's disease. 7891887

1994
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C1863051
Disease: ALZHEIMER DISEASE 2
ALZHEIMER DISEASE 2 		0.800 GeneticVariation UNIPROT Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. 8346443

1993
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C1863051
Disease: ALZHEIMER DISEASE 2
ALZHEIMER DISEASE 2 		0.800 GeneticVariation UNIPROT Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease. 8367470

1993
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C1863051
Disease: ALZHEIMER DISEASE 2
ALZHEIMER DISEASE 2 		0.800 GeneticVariation UNIPROT Nucleotide sequence and structure of the human apolipoprotein E gene. 2987927

1985