Source: BEFREE

Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs115881343
rs115881343
TOMM40
1.000 0.040 19 44899959 intron variant C/G;T snv 2.9E-02
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.710 1.000 1 2014 2014
dbSNP: rs429358
rs429358
APOE
0.590 0.600 19 44908684 missense variant T/C snv 0.14 0.16
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.710 1.000 1 2017 2019
dbSNP: rs4420638
rs4420638
APOC1
0.708 0.520 19 44919689 downstream gene variant A/G snv 0.18
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.710 1.000 1 2012 2019
dbSNP: rs769449
rs769449
APOE
0.882 0.120 19 44906745 non coding transcript exon variant G/A snv 8.4E-02
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.710 1.000 1 2014 2014
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.436 0.760 11 27658369 missense variant C/T snv 0.19 0.15
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.080 1.000 8 2006 2020
dbSNP: rs759834365
rs759834365
BDNF ; BDNF-AS
0.448 0.760 11 27658456 missense variant C/T snv 1.2E-05
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.070 1.000 7 2006 2020
dbSNP: rs1217691063
rs1217691063
MTHFR
0.330 0.920 1 11796309 missense variant A/G snv 4.0E-06 7.0E-06
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.040 1.000 4 2007 2019
dbSNP: rs1801282
rs1801282
PPARG
0.500 0.840 3 12351626 missense variant C/G snv 0.11 8.9E-02
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.040 1.000 4 2008 2019
dbSNP: rs1805192
rs1805192
PPARG
0.510 0.840 3 12379739 missense variant C/G snv
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.040 1.000 4 2008 2019
dbSNP: rs17125721
rs17125721
PSEN1
0.763 0.120 14 73206470 missense variant A/G snv 1.5E-02 1.5E-02
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.020 1.000 2 2002 2013
dbSNP: rs1800764
rs1800764 		0.790 0.320 17 63473168 upstream gene variant C/G;T snv
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.020 1.000 2 2014 2014
dbSNP: rs4680
rs4680
COMT ; MIR4761
0.442 0.920 22 19963748 missense variant G/A snv 0.46 0.44
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.020 1.000 2 2018 2019
dbSNP: rs5882
rs5882
CETP
0.649 0.400 16 56982180 missense variant G/A;C snv 0.62
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.020 1.000 2 2012 2015
dbSNP: rs63750847
rs63750847
APP
0.790 0.120 21 25897620 missense variant C/T snv 4.5E-04 3.0E-04
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.020 1.000 2 2012 2018
dbSNP: rs1049564
rs1049564
PNP
0.882 0.160 14 20472447 missense variant G/A snv 0.19 0.21
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.010 1.000 1 2007 2007
dbSNP: rs10524523
rs10524523
TOMM40
0.807 0.200 19 44899792 intron variant TTTTTTTTTTTTTTTTTTTTTTT/-;T;TT;TTT;TTTT;TTTTT;TTTTTT;TTTTTTT;TTTTTTTT;TTTTTTTTT;TTTTTTTTTT;TTTTTTTTTTT;TTTTTTTTTTTT;TTTTTTTTTTTTT;TTTTTTTTTTTTTT;TTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT;TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT delins
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.010 1.000 1 2017 2017
dbSNP: rs11030108
rs11030108
BDNF ; BDNF-AS
1.000 0.040 11 27673917 intron variant A/G snv 0.72
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.010 1.000 1 2013 2013
dbSNP: rs11136000
rs11136000
CLU
0.752 0.160 8 27607002 intron variant T/C snv 0.56
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.010 1.000 1 2013 2013
dbSNP: rs112422930
rs112422930
MUTYH
0.882 0.160 1 45332409 missense variant A/C snv 7.0E-06
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.010 1.000 1 2011 2011
dbSNP: rs1126680
rs1126680
BCHE
0.851 0.160 3 165837337 synonymous variant C/T snv 5.6E-02 5.6E-02
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.010 1.000 1 2019 2019
dbSNP: rs1143684
rs1143684
NQO2
0.882 0.160 6 3010156 missense variant C/T snv 0.79 0.84
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.010 1.000 1 2010 2010
dbSNP: rs1157659
rs1157659 		1.000 0.040 11 27736075 intron variant A/G snv 0.37
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.010 1.000 1 2013 2013
dbSNP: rs1187120
rs1187120 		0.925 0.040 6 34182850 intergenic variant T/C snv 0.99
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.010 1.000 1 2015 2015
dbSNP: rs11887120
rs11887120
DNMT3A
0.882 0.080 2 25262866 intron variant C/T snv 0.45
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.010 < 0.001 1 2016 2016
dbSNP: rs1206642175
rs1206642175
ESR1
0.925 0.080 6 151808263 synonymous variant G/A snv 7.0E-06
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.010 1.000 1 2008 2008