Source: BEFREE

Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs3758391
rs3758391
SIRT1
0.742 0.480 10 67883584 upstream gene variant T/C snv 0.64
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.030 0.667 3 2010 2020
dbSNP: rs7896005
rs7896005
SIRT1
0.925 0.080 10 67891367 intron variant A/G;T snv 0.52; 8.0E-06 0.47
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.030 1.000 3 2011 2020
dbSNP: rs10823108
rs10823108
SIRT1
0.925 0.160 10 67900736 intron variant G/A snv 7.1E-02
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.020 1.000 2 2017 2018
dbSNP: rs12778366
rs12778366
SIRT1
0.724 0.480 10 67883321 upstream gene variant T/C;G snv
CUI: C0242383
Disease: Age related macular degeneration
Age related macular degeneration 		0.020 1.000 2 2015 2019
dbSNP: rs12778366
rs12778366
SIRT1
0.724 0.480 10 67883321 upstream gene variant T/C;G snv
CUI: C0032000
Disease: Pituitary Adenoma
Pituitary Adenoma 		0.020 1.000 2 2017 2019
dbSNP: rs1467568
rs1467568
SIRT1
0.776 0.320 10 67915401 intron variant A/G snv 0.46
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.020 1.000 2 2017 2018
dbSNP: rs2273773
rs2273773
SIRT1
0.790 0.360 10 67906841 synonymous variant T/C snv 0.11 7.1E-02
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.020 1.000 2 2011 2015
dbSNP: rs7069102
rs7069102
SIRT1
0.790 0.440 10 67903362 intron variant C/G snv 0.64
CUI: C0028754
Disease: Obesity
Obesity 		0.020 1.000 2 2008 2011
dbSNP: rs10823108
rs10823108
SIRT1
0.925 0.160 10 67900736 intron variant G/A snv 7.1E-02
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 1.000 1 2017 2017
dbSNP: rs10997870
rs10997870
SIRT1
1.000 0.040 10 67908257 intron variant G/T snv 0.47
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.010 1.000 1 2016 2016
dbSNP: rs10997870
rs10997870
SIRT1
1.000 0.040 10 67908257 intron variant G/T snv 0.47
CUI: C0086132
Disease: Depressive Symptoms
Depressive Symptoms 		0.010 1.000 1 2016 2016
dbSNP: rs10997871
rs10997871
SIRT1
0.925 0.080 10 67913178 intron variant T/C snv 4.1E-03
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.010 1.000 1 2019 2019
dbSNP: rs10997871
rs10997871
SIRT1
0.925 0.080 10 67913178 intron variant T/C snv 4.1E-03
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.010 1.000 1 2019 2019
dbSNP: rs10997871
rs10997871
SIRT1
0.925 0.080 10 67913178 intron variant T/C snv 4.1E-03
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.010 1.000 1 2019 2019
dbSNP: rs11599176
rs11599176
SIRT1
0.925 0.080 10 67894017 intron variant A/G snv 0.11
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic 		0.010 1.000 1 2018 2018
dbSNP: rs11599176
rs11599176
SIRT1
0.925 0.080 10 67894017 intron variant A/G snv 0.11
CUI: C0400966
Disease: Non-alcoholic Fatty Liver Disease
Non-alcoholic Fatty Liver Disease 		0.010 1.000 1 2018 2018
dbSNP: rs12413112
rs12413112
SIRT1
1.000 0.040 10 67892108 intron variant G/A snv 0.11
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.010 1.000 1 2018 2018
dbSNP: rs12778366
rs12778366
SIRT1
0.724 0.480 10 67883321 upstream gene variant T/C;G snv
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.010 1.000 1 2016 2016
dbSNP: rs12778366
rs12778366
SIRT1
0.724 0.480 10 67883321 upstream gene variant T/C;G snv
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.010 1.000 1 2016 2016
dbSNP: rs12778366
rs12778366
SIRT1
0.724 0.480 10 67883321 upstream gene variant T/C;G snv
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.010 1.000 1 2018 2018
dbSNP: rs12778366
rs12778366
SIRT1
0.724 0.480 10 67883321 upstream gene variant T/C;G snv
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.010 1.000 1 2018 2018
dbSNP: rs12778366
rs12778366
SIRT1
0.724 0.480 10 67883321 upstream gene variant T/C;G snv
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.010 1.000 1 2018 2018
dbSNP: rs12778366
rs12778366
SIRT1
0.724 0.480 10 67883321 upstream gene variant T/C;G snv
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.010 1.000 1 2019 2019
dbSNP: rs12778366
rs12778366
SIRT1
0.724 0.480 10 67883321 upstream gene variant T/C;G snv
CUI: C0280324
Disease: Laryngeal Squamous Cell Carcinoma
Laryngeal Squamous Cell Carcinoma 		0.010 1.000 1 2019 2019
dbSNP: rs12778366
rs12778366
SIRT1
0.724 0.480 10 67883321 upstream gene variant T/C;G snv
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.010 1.000 1 2014 2014