Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Obesity-associated gene FTO rs9939609 polymorphism in relation to the risk of tuberculosis. 25377722

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE rs9939609 in the FTO gene is associated with obesity but not with several biochemical parameters in Sardinian obese children. 21913894

2011

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE A case-control association analysis revealed that 15 SNPs, including rs9939609 and rs1121980, in a linkage disequilibrium (LD) block of approximately 50 kb demonstrated significant associations with obesity; rs1558902 was most significantly associated with obesity. 18379722

2008

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE A dose-response relationship was found between the number of risk alleles in rs7206790, rs11644943 and rs9939609 and the risk of obesity. 25251416

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE A meta-analysis of the four studies showed a significant inverse association between the obesity risk FTO rs9939609 A variant and depression (odds ratio=0.92 (0.89, 0.97), P=3 × 10(-4)) adjusted for age, sex, ethnicity/population structure and body-mass index (BMI) with no significant between-study heterogeneity (I(2)=0%, P=0.63). 23164817

2013

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE A minimal gata2 promoter-GFP cassette was inserted 1.3 kb upstream of the obesity associated SNP rs9939609 in a human FTO BAC plasmid. 26271004

2015

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE A recent genome-wide association study showed that the rs9939609 polymorphism in the fat mass and obesity-associated (FTO) gene was associated with body mass index (BMI)/obesity in Europeans. 22396042

2012

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE A region in the first intron of the fat mass- and obesity-associated (FTO) gene, encompassing markers rs9939973, rs8050136, and rs9939609, has been consistently associated with obesity and body mass index (BMI) in different populations. 26529281

2015

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Among the 19 SNPs, the rs9939609 A allele was strongly associated with obesity (P = 7.0 x 10(-4)) and BMI (P = 0.0024) in the Chinese population. 18487448

2008

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Analysis of vitamin D receptor (VDR) TaqI (rs731236; T/C) and fat mass and obesity-associated (FTO) (rs9939609; A/T) [corrected] polymorphisms in 82 obesity subjects and 102 controls showed significant association for VDR TaqI 'T' allele and obesity (OR: 2.07; 1.123-3.816; P=0.019), contributing to an elevated BMI of 3kg/m(2) per risk allele. 23103831

2013

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Association between overweight and obesity in schoolchildren with rs9939609 polymorphism (FTO) and family history for obesity. 27154418

2017

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Association of obesity with rs1421085 and rs9939609 polymorphisms of FTO gene. 25074273

2014

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Association of rs9939609 variant with higher FBG, plasma insulin, and leptin levels indicates that this polymorphism may disturb the metabolism in adult females and predispose them to obesity and type 2 diabetes. 24102053

2013

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Associations between an obesity related genetic variant (FTO rs9939609) and prostate cancer risk. 20976066

2010

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Children with the FTO (rs9939609) variant that increases the risk of obesity may have a higher susceptibility to the effects of DED because their internal appetite control system is compromised. 19259258

2009

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE DNA samples were genotyped for the rs9939609 polymorphism in the obesity-linked gene <i>FTO</i>. 30759834

2019

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Education modulates the association of the FTO rs9939609 polymorphism with body mass index and obesity risk in the Mediterranean population. 21186106

2012

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Fat mass and obesity-associated gene (FTO) in eating disorders: evidence for association of the rs9939609 obesity risk allele with bulimia nervosa and anorexia nervosa. 22797368

2012

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Findings of the present study highlight the association between FTO rs9939609 and obesity or body fat indices in girls but not in boys. 31444941

2019

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE For white participants, the FTO rs9939609 A allele was associated with an increased risk of diabetes (odds ratio (OR) = 1.19, p<0.001) and obesity (OR = 1.22, p<0.001) under an additive genetic model that was similar for all of the SNPs analyzed. 20502638

2010

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE Four polymorphisms (rs9935401, rs9939609, rs9928094 and rs9930333) were positively associated with obesity and in linkage disequilibrium between each other; the haplotype including the risk alleles of these polymorphisms showed a high risk for obesity. 24289790

2013

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE FTO rs9939609 was associated with higher body mass index (BMI), waist circumference (WC) and obesity (P<0.05 for all). 23284998

2012

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE FTO rs9939609 polymorphism is associated with the increased risk of obesity among children and adolescents, especially the homozygous carriers. 25753879

2015

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE FTO rs9939609 is associated with obesity risk and LTL in this study, where this association is only observed at higher, but not lower, FTO methylation levels of participants. 28559540

2017

dbSNP: rs9939609
rs9939609
FTO
CUI: C0028754
Disease: Obesity
Obesity
0.800 GeneticVariation BEFREE FTO rs9939609 was associated with risk of obesity in additive model (p=0.031), recessive (p=0.033) and with altered WC in all models. 30713021

2020