rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
FTO rs9939609 was associated with risk of obesity in additive model (p=0.031), recessive (p=0.033) and with altered WC in all models.
|
30713021 |
2020 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
FTO rs9939609 had an obvious and independent effect on obesity-related indices in early adolescents.
|
31402168 |
2020 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
We focused on rs7185735 and rs9939609, 2 common single nucleotide polymorphisms of the fat mass and obesity-associated (FTO) gene reported to be associated with obesity.
|
29334686 |
2019 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
Findings of the present study highlight the association between FTO rs9939609 and obesity or body fat indices in girls but not in boys.
|
31444941 |
2019 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
The FTO gene polymorphism rs9939609 is associated with obesity and disability in multiple sclerosis patients.
|
31836807 |
2019 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
Of interest, a markedly lower frequency of the FTO rs9939609 obesity risk A-allele was found in BED patients (0.290) in relation to the control group (0.402).
|
30677719 |
2019 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
The FTO rs9939609 polymorphism and obesity risk in teens: Evidence-based meta-analysis.
|
30104138 |
2019 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
Psoriatic patients, carriers of risk allele of <i>FTO</i> gene rs9939609, have an increased risk for more severe psoriasis and obesity and may develop obesity-induced insulin resistance.
|
30733965 |
2019 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
The rs9939609 affected the response to dietary intervention in obese women: A allele carriers reduced 2.7 cm less of abdominal circumference (AC) than homozygous TT (p = 0.04), while no effect was observed in response to physical exercise in overweight and obese children and adolescents.
|
29238857 |
2019 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
DNA samples were genotyped for the rs9939609 polymorphism in the obesity-linked gene <i>FTO</i>.
|
30759834 |
2019 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
These findings suggest that Indonesian adults with AT/AA genotypes of the FTO rs9939609 have higher obesity risks and preferences for high dietary fat intake than those with TT genotype.
|
30896430 |
2019 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
The rs9939609 polymorphism of the fat mass and obesity-associated (FTO) gene has been associated with obesity, and studies have also shown that environmental/lifestyle interaction such as dietary intake might mediate this effect.
|
31635368 |
2019 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
The fat mass and obesity-associated gene (FTO) rs9939609 A-allele is associated with higher acyl-ghrelin (AG) concentrations, higher energy intake, and obesity, although exercise may mitigate rs9939609 A-allele-linked obesity risk.
|
31504106 |
2019 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
Our results suggested that FTO rs9939609, MC4R rs12970134, and MC4R rs17782313 are strongly associated with obesity.
|
30896429 |
2019 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
The fat mass and obesity-related (FTO) single-nucleotide polymorphism (SNP) rs9939609 is a major SNP associated with obesity and has been used as an instrumental variable for obesity in a Mendelian randomization (MR) approach.
|
31401654 |
2019 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
The aim of this study is to investigate whether the genetic risk score (GRS) based on previously associated obesity polymorphisms (SNP) rs9939609 (fat mass and obesity-associated (FTO)), rs6548238 (transmembrane protein 18 (TMEM18)) and rs16835198 (fibronectin type III domain containing 5 (FNDC5)) could serve as a predictor for anthropometric characteristics in a sample of Brazilian children and adolescents.
|
30311592 |
2019 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
FTO SNPs rs1421085 and rs9939609 affect genetic susceptibility for obesity only in girls, whereas, SNP rs8057044 and CNV are associated with overweight status only in boys.
|
30537186 |
2019 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
We investigated a </span>possible association of ADIPOQ rs2241766 G>T, FTO rs9939609</span> A>T and ACE rs4340288 DIP variants among obese and non-obese Turkish Cypriot origin.
|
30416093 |
2019 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
The FTO polymorphisms were associated with a significantly increased risk for obesity and in BMI-stratified cohort, rs9939609 (T/A: odds ratio [OR] = 1.73, p = 0.007) and rs1421085 (T/C: OR = 1.56, p = 0.03) showed even stronger association.
|
29466028 |
2018 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
We observed an association between the common FTO rs9939609 polymorphism and increased BMI (overweight/obesity) in Kuwaiti adults, which is consistent with previous research in other populations.
|
29402776 |
2018 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
MAF of G2548A was 42.8% in obese and 30.1% in controls (<i>P</i>=5.7 × 10<sup>-5</sup>), it showed association with weight, body mass index (BMI), waist circumference (WC), high density lipoprotein cholesterol (HDL-c) and leptin, Gln223Arg had MAF 32% in obese and 18.7% in controls (<i>P</i>=5.4 × 10<sup>-6</sup>), it showed association with fasting plasma glucose (FPG) and all lipid traits, Ala54Thr had MAF 42.4% in obese and 33.1% (<i>P</i>=0.002), it showed association with none of the tested parameters. rs9939609 MAF was 26.6%, and showed association with none of the tested parameters. rs1802295 (<i>P</i>=0.002); rs7178572 (<i>P</i>=0.007); rs2028299 (<i>P</i>=0.04); rs4812829 (<i>P</i>=0.02) showed significant while rs3923113 and rs16861329 did not show a significant association (<i>P</i>=0.20 and <i>P</i>=0.3, respectively) with obesity.
|
29752338 |
2018 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
To examine the associations of two obesity-associated genes, FTO (rs9939609) and GNB3 (rs5443) single nucleotide polymorphisms (SNPs), with early pregnancy body mass index, gestational weight gain, and postpartum weight retention.
|
29469022 |
2018 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
We performed a cross-sectional study in a sample that was enriched for obesity and included 20 higher-risk participants with the AA (risk) genotype at the rs9939609 locus of FTO and 94 lower-risk participants with either the AT or TT genotype.
|
29529147 |
2018 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
To the best of the author's knowledge this is the first study, associating FTO rs9939609</span> gene polymorphism and obesity in the North-eastern Indian tribal populations with East-Asian ancestry.
|
29317321 |
2018 |
rs9939609
|
|
Obesity
|
|
0.800 |
GeneticVariation
|
BEFREE |
The risk of obesity in Mongolian individuals carrying rs</span>9939609 AT genotype was 1.312 times higher and the risk in those carrying AA genotype was 1.896 times higher than in individuals with TT genotype.
|
30442880 |
2018 |