Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs778561687
rs778561687
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
T 0.700 GeneticVariation CLINVAR AKT1 and AKT2 mutations in lung cancer in a Japanese population. 21479466

2012

dbSNP: rs778561687
rs778561687
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
T 0.700 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968

2014

dbSNP: rs113488022
rs113488022
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
T 0.800 CausalMutation CLINVAR Mutations of the BRAF gene in human cancer. 12068308

2002

dbSNP: rs121913355
rs121913355
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
A 0.720 CausalMutation CLINVAR Mutations of the BRAF gene in human cancer. 12068308

2002

dbSNP: rs121913355
rs121913355
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
G 0.720 CausalMutation CLINVAR Mutations of the BRAF gene in human cancer. 12068308

2002

dbSNP: rs121913357
rs121913357
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
T 0.710 GeneticVariation CLINVAR Mutations of the BRAF gene in human cancer. 12068308

2002

dbSNP: rs727502902
rs727502902
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
TGTA 0.700 CausalMutation CLINVAR Prognostic and clinicopathologic associations of oncogenic BRAF in metastatic melanoma. 21343559

2011

dbSNP: rs727502902
rs727502902
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
TGTA 0.700 CausalMutation CLINVAR Functional characterization of a BRAF insertion mutant associated with pilocytic astrocytoma. 21190184

2011

dbSNP: rs727502902
rs727502902
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
TGTA 0.700 CausalMutation CLINVAR Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma. 19363522

2009

dbSNP: rs727502902
rs727502902
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
TGTA 0.700 CausalMutation CLINVAR BRAF, p53 and SOX2 in anaplastic thyroid carcinoma: evidence for multistep carcinogenesis. 21716161

2011

dbSNP: rs727502902
rs727502902
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
TGTA 0.700 CausalMutation CLINVAR Distinguishing clinicopathologic features of patients with V600E and V600K BRAF-mutant metastatic melanoma. 22535154

2012

dbSNP: rs727502902
rs727502902
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
TGTA 0.700 CausalMutation CLINVAR Alterations of BRAF and HIPK2 loci predominate in sporadic pilocytic astrocytoma. 19794125

2009

dbSNP: rs397516897
rs397516897
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
T 0.700 GeneticVariation CLINVAR Mutations of the BRAF gene in human cancer. 12068308

2002

dbSNP: rs397516896
rs397516896
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
T 0.700 GeneticVariation CLINVAR NRAS and BRAF mutations in melanoma tumours in relation to clinical characteristics: a study based on mutation screening by pyrosequencing. 17119447

2006

dbSNP: rs397516896
rs397516896
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
T 0.700 GeneticVariation CLINVAR KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradiotherapy. 19913317

2010

dbSNP: rs397516896
rs397516896
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
T 0.700 GeneticVariation CLINVAR B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis. 17311103

2007

dbSNP: rs397516896
rs397516896
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
T 0.700 GeneticVariation CLINVAR Gene expression signature associated with BRAF mutations in human primary cutaneous melanomas. 19383316

2008

dbSNP: rs397516896
rs397516896
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
T 0.700 GeneticVariation CLINVAR Mutations of the BRAF gene in human cancer. 12068308

2002

dbSNP: rs397516896
rs397516896
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
T 0.700 GeneticVariation CLINVAR Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer. 17096326

2007

dbSNP: rs397516896
rs397516896
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
T 0.700 GeneticVariation CLINVAR MC1R variants increase risk of melanomas harboring BRAF mutations. 18368129

2008

dbSNP: rs397516890
rs397516890
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
T 0.700 CausalMutation CLINVAR

dbSNP: rs121913378
rs121913378
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
A 0.700 GeneticVariation CLINVAR High frequency of mutations of the PIK3CA gene in human cancers. 15016963

2004

dbSNP: rs121913378
rs121913378
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
A 0.700 GeneticVariation CLINVAR Inactivation of the mitogen-activated protein kinase pathway as a potential target-based therapy in ovarian serous tumors with KRAS or BRAF mutations. 15753399

2005

dbSNP: rs121913378
rs121913378
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
T 0.700 GeneticVariation CLINVAR

dbSNP: rs121913370
rs121913370
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma
C 0.700 GeneticVariation CLINVAR