|
rs1801133
|
|
Malignant neoplasm of breast
|
|
0.100 |
GeneticVariation
|
BEFREE |
Association of 677 C>T (rs1801133) and 1298 A>C (rs1801131) polymorphisms in the MTHFR gene and breast cancer susceptibility: a meta-analysis based on 57 individual studies.
|
24945727 |
2014 |
|
rs1801133
|
|
Breast Carcinoma
|
|
0.100 |
GeneticVariation
|
BEFREE |
Association of 677 C>T (rs1801133) and 1298 A>C (rs1801131) polymorphisms in the MTHFR gene and breast cancer susceptibility: a meta-analysis based on 57 individual studies.
|
24945727 |
2014 |
|
rs1801133
|
|
Mental Depression
|
|
0.020 |
GeneticVariation
|
BEFREE |
Association of C677T polymorphism (rs1801133) in MTHFR gene with depression.
|
28968218 |
2017 |
|
rs1801133
|
|
Depressive disorder
|
|
0.020 |
GeneticVariation
|
BEFREE |
Association of C677T polymorphism (rs1801133) in MTHFR gene with depression.
|
28968218 |
2017 |
|
rs1801133
|
|
Depressed mood
|
|
0.020 |
GeneticVariation
|
BEFREE |
Association of C677T polymorphism (rs1801133) in MTHFR gene with depression.
|
28968218 |
2017 |
|
rs1801133
|
|
Sporadic Parkinson disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
Association of the rs1801133 variant in the MTHFR gene and sporadic Parkinson's disease.
|
25909872 |
2015 |
|
rs1801133
|
|
Sporadic Parkinson disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
Association of the MTHFR rs1801131 and rs1801133 variants in sporadic Parkinson's disease patients.
|
26806866 |
2016 |
|
rs1801133
|
|
Rheumatoid Arthritis
|
|
0.050 |
GeneticVariation
|
BEFREE |
Associations between asymmetric dimethylarginine, homocysteine, and the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism (rs1801133) in rheumatoid arthritis.
|
26599798 |
2016 |
|
rs1801133
|
|
Vascular cognitive impairment
|
|
0.020 |
GeneticVariation
|
BEFREE |
Associations of increased risk for VCI were found for APOE ε4 (1.818 (95% CI = 1.611-2.053), p < 0.001; n = 3,554 cases, n = 12,277 controls) and MTHFR rs1801133 (1.323 (95% CI = 1.061-1.650) p = 0.013); n = 659 cases, n = 981 controls).
|
23186985 |
2013 |
|
rs1801133
|
|
Coronary heart disease
|
|
0.040 |
GeneticVariation
|
BEFREE |
Associations of the MTHFR rs1801133 polymorphism with coronary artery disease and lipid levels: a systematic review and updated meta-analysis.
|
30115070 |
2018 |
|
rs1801133
|
|
Coronary Arteriosclerosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
Associations of the MTHFR rs1801133 polymorphism with coronary artery disease and lipid levels: a systematic review and updated meta-analysis.
|
30115070 |
2018 |
|
rs1801133
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.050 |
GeneticVariation
|
BEFREE |
At present, adequate data is not available dealing with MTHFR (rs1801133) and PPARγ2 (rs1801282) gene polymorphisms and its association with type 2 diabetes mellitus cases among north Indian populations.
|
23036708 |
2012 |
|
rs1801133
|
|
Cognitive changes
|
|
0.010 |
GeneticVariation
|
BEFREE |
Both the 677C>T (rs1801133) polymorphism and the scarcely studied 1298A>C (rs1801131) polymorphism of the MTHFR gene were assessed in relation to cognitive change over 8 years in older community-dwelling individuals.
|
21255267 |
2011 |
|
rs1801133
|
|
Migraine Disorders
|
|
0.020 |
GeneticVariation
|
BEFREE |
By multivariate logistic stepwise regression analysis, type of migraine, regular and sufficient dietary intake, and methylenetetrahydrofolate reductase (MTHFR) C677T (rs1801133) and dopamine D2 receptor (DRD2) C939T (rs6275) polymorphisms were selected as significant factors that contribute independently to the development from migraine to MOH (P < 0.05).
|
22290307 |
2013 |
|
rs1801133
|
|
Analgesic Overuse Headache
|
|
0.010 |
GeneticVariation
|
BEFREE |
By multivariate logistic stepwise regression analysis, type of migraine, regular and sufficient dietary intake, and methylenetetrahydrofolate reductase (MTHFR) C677T (rs1801133) and dopamine D2 receptor (DRD2) C939T (rs6275) polymorphisms were selected as significant factors that contribute independently to the development from migraine to MOH (P < 0.05).
|
22290307 |
2013 |
|
rs1801133
|
|
Juvenile arthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
C677T (rs1801133) polymorphism in MTHFR predicts nonresponse and/or adverse effects of MTX treatment in JIA patients.
|
29589488 |
2018 |
|
rs1801133
|
|
Acrocyanosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Chronic idiopathic acrocyanosis and methylenetetrahydrofolate reductase C677T (p.Ala222Val) and A1298C (p.Glu429Ala) polymorphisms.
|
23816603 |
2015 |
|
rs1801133
|
|
Parkinson Disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
Collectively, our meta-analysis suggests that rs1801133 is significantly associated with susceptibility to PD in European and Asian populations, and MTHFR is likely an authentic risk gene for PD.
|
23916622 |
2013 |
|
rs1801133
|
|
Homocysteine measurement
|
A |
0.800 |
GeneticVariation
|
GWASCAT |
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.
|
23824729 |
2013 |
|
rs1801133
|
|
Homocysteine measurement
|
A |
0.800 |
GeneticVariation
|
GWASDB |
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.
|
23824729 |
2013 |
|
rs1801133
|
|
Rumination Disorders
|
|
0.010 |
GeneticVariation
|
BEFREE |
Despite its functional effect on folate metabolism, the MTHFR rs1801133 showed no effect on rumination.
|
26926881 |
2016 |
|
rs1801133
|
|
Psychotic Disorders
|
|
0.010 |
GeneticVariation
|
BEFREE |
Disorganization is associated with early schizophrenia onset and history of psychosis in family, low level of insight and compliance, high risk of committing delicts, distraction errors in WCST, lengthened P300 latency of evoked cognitive auditory potentials, low-functional alleles of genes MTHFR (rs1801133) and DNMT3b (rs2424913), high level of urbanicity and psychotraumatic events at early age.
|
28192769 |
2017 |
|
rs1801133
|
|
Nonorganic psychosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Disorganization is associated with early schizophrenia onset and history of psychosis in family, low level of insight and compliance, high risk of committing delicts, distraction errors in WCST, lengthened P300 latency of evoked cognitive auditory potentials, low-functional alleles of genes MTHFR (rs1801133) and DNMT3b (rs2424913), high level of urbanicity and psychotraumatic events at early age.
|
28192769 |
2017 |
|
rs1801133
|
|
Liver carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
Donor MTHFR rs1801133 C to T polymorphism could present as a promising prognostic biomarkers for HCC recurrence in liver transplant recipients.
|
29185200 |
2018 |
|
rs1801133
|
|
Childhood Acute Lymphoblastic Leukemia
|
|
0.030 |
GeneticVariation
|
BEFREE |
Due to the importance of the transport P-glycoprotein and methylenetetrahydrofolate reductase in the metabolism of chemotherapeutic agents, we analyzed the MDR1 rs1045642 and MTHFR rs1801133 polymorphisms and their associations with clinical outcomes in Mexican childhood ALL patients.
|
27533339 |
2016 |