Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs17782313
rs17782313
CUI: C0028754
Disease: Obesity
Obesity
0.900 GeneticVariation BEFREE Our study pointed out the role of MC4R rs17782313 and ENPP1 rs1044498 genotypes in obesity determinisms in mothers and their newborns in correlation with BMI, MUAC, TST and bioimpedance parameters. 31350533

2019

dbSNP: rs17782313
rs17782313
CUI: C0028754
Disease: Obesity
Obesity
0.900 GeneticVariation BEFREE Rs9939609 and rs17782313 are associated with PCOS and obesity-related traits and profiles. 26032905

2015

dbSNP: rs17782313
rs17782313
CUI: C0028754
Disease: Obesity
Obesity
0.900 GeneticVariation BEFREE We have previously demonstrated that three obesity-susceptible single nucleotide polymorphisms (SNPs), rs10938397 (GNPDA2), rs8050136 (FTO) and rs17782313 (MC4R), were associated with obesity and waist circumference in cross-sectional studies in the Chinese population. 21147891

2011

dbSNP: rs17782313
rs17782313
CUI: C0028754
Disease: Obesity
Obesity
0.900 GeneticVariation BEFREE <i>Purpose</i>.Genome-wide association studies have found two obesity-related single-nucleotide polymorphisms (SNPs), rs17782313 near the melanocortin-4 receptor (<i>MC4R</i>) gene and rs6265 near the brain-derived neurotrophic factor (<i>BDNF</i>) gene, but the associations of both SNPs with other obesity-related traits are not fully described, especially in children. 28396685

2017

dbSNP: rs17782313
rs17782313
CUI: C0028754
Disease: Obesity
Obesity
0.900 GeneticVariation BEFREE To further elucidate the role of genetics in obesity onset, we performed a candidate-gene association study in a young and sportive Italian population by testing the association of functional polymorphisms in ACE (rs4646994), FTO (rs9939609), MC4R (rs17782313) and PPARG (rs1801282) genes with body mass index (BMI) and waist-to-height ratio (WHtR). 28090739

2017

dbSNP: rs17782313
rs17782313
CUI: C0028754
Disease: Obesity
Obesity
0.900 GeneticVariation BEFREE Genetic variants of the FTO gene rs9939609 A/T and the MC4R gene rs17782313 C/T have been associated with obesity. 23849767

2013

dbSNP: rs17782313
rs17782313
CUI: C0028754
Disease: Obesity
Obesity
0.900 GeneticVariation BEFREE MC4R rs17782313 was associated with obesity and could confer a certain susceptibility to T2D that could be independent of its pro-obesity effect. 24151814

2014

dbSNP: rs17782313
rs17782313
CUI: C0028754
Disease: Obesity
Obesity
0.900 GeneticVariation BEFREE The results suggested that rs17782313 polymorphism was significantly associated with obesity risk (OR=1.18, 95%CI=1.15-1.21, p<0.001). 23049848

2012

dbSNP: rs17782313
rs17782313
CUI: C0028754
Disease: Obesity
Obesity
0.900 GeneticVariation BEFREE Genome-wide association studies have shown that variants near the melanocortin 4 receptor gene (MC4R) (rs17782313 and rs12970134) are associated with risk of obesity in Europeans. 22869321

2012

dbSNP: rs17782313
rs17782313
CUI: C0028754
Disease: Obesity
Obesity
0.900 GeneticVariation BEFREE After age and sex adjustment and correction for multiple testing, the SNPs rs17782313, rs6265, and rs10938397 were associated with BMI (P = 1.0 × 10⁻⁵, 0.038, and 0.00093, respectively) and also obesity (P = 5.0 × 10⁻⁶, 0.043, and 0.00085, respectively) in the Chinese children. 20843981

2010

dbSNP: rs17782313
rs17782313
CUI: C0028754
Disease: Obesity
Obesity
0.900 GeneticVariation BEFREE Melanocortin-4 receptor polymorphism rs17782313: association with obesity and eating in the absence of hunger in Chilean children. 24139164

2014

dbSNP: rs17782313
rs17782313
CUI: C0028754
Disease: Obesity
Obesity
0.900 GeneticVariation BEFREE Our aim was to identify whether the obesity-susceptible gene variants (rs9939609, rs9930506, and rs4783819 in fat mass and obesity-associated gene (FTO); rs12970134 and rs17782313 in melanocortin-4 receptor gene (MC4R); and rs7566605, rs13428113, and rs9308762 in insulin-induced gene 2 [INSIG2]) were associated with NAFLD. 24458218

2014

dbSNP: rs17782313
rs17782313
CUI: C0028754
Disease: Obesity
Obesity
0.900 GeneticVariation BEFREE To study the association of rs9939609 (FTO) and rs17782313 (MC4R) to obesity related anthropometric traits in Indian adolescents. 23447422

2013

dbSNP: rs17782313
rs17782313
CUI: C0028754
Disease: Obesity
Obesity
0.900 GeneticVariation BEFREE Recently a modest, but consistently, replicated association was demonstrated between obesity and the single-nucleotide polymorphism (SNP), rs17782313, 3' of the MC4R locus as a consequence of a meta-analysis of genome-wide association (GWA) studies of the disease in white populations. 19265794

2009

dbSNP: rs17782313
rs17782313
CUI: C0028754
Disease: Obesity
Obesity
0.900 GeneticVariation BEFREE To investigate the association between the fat mass and obesity related (FTO) gene rs9939609 and near melanocortin-4-receptor (MC4R) gene rs17782313 polymorphisms with obesity measures and metabolic parameters in urban and rural dwelling Sri Lankans. 26948330

2016

dbSNP: rs17782313
rs17782313
CUI: C0028754
Disease: Obesity
Obesity
0.900 GeneticVariation BEFREE Analysis of MC4R rs17782313, POMC rs1042571, APOE-Hha1 and AGRP rs3412352 genetic variants with susceptibility to obesity risk in North Indians. 26226973

2016