Source: GWASDB

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1333040
rs1333040
CDKN2B-AS1
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		T 0.840 GeneticVariation GWASDB Genome-wide association study of intracranial aneurysm identifies three new risk loci. 20364137

2010
dbSNP: rs1333040
rs1333040
CDKN2B-AS1
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		T 0.840 GeneticVariation GWASDB Susceptibility loci for intracranial aneurysm in European and Japanese populations. 18997786

2008
dbSNP: rs9298506
rs9298506
RP1
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		A 0.830 GeneticVariation GWASDB Genome-wide association study of intracranial aneurysm identifies three new risk loci. 20364137

2010
dbSNP: rs9298506
rs9298506
RP1
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		A 0.830 GeneticVariation GWASDB Susceptibility loci for intracranial aneurysm in European and Japanese populations. 18997786

2008
dbSNP: rs10757272
rs10757272
CDKN2B-AS1
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		T 0.820 GeneticVariation GWASDB Additionally, we successfully replicated and validated rs10757272 on CDKN2BAS at chromosome 9p21.3 (combined P-value = 1.55 × 10(-7); odds ratio = 1.21) to be significantly associated with IA as previously reported. 22286173

2012
dbSNP: rs10958409
rs10958409
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		0.820 GeneticVariation GWASDB Genome-wide association study of intracranial aneurysm identifies three new risk loci. 20364137

2010
dbSNP: rs10958409
rs10958409
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		A 0.820 GeneticVariation GWASDB Susceptibility loci for intracranial aneurysm in European and Japanese populations. 18997786

2008
dbSNP: rs700651
rs700651
BOLL
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		G 0.820 GeneticVariation GWASDB Susceptibility loci for intracranial aneurysm in European and Japanese populations. 18997786

2008
dbSNP: rs6475606
rs6475606
CDKN2B-AS1
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		T 0.810 GeneticVariation GWASDB However, the metaanalysis yielded genomewide significance for SNP on chromosome 9p (CDKN2BAS; rs6475606; P=3.6×10(-8)) and provided further evidence to support the previously reported association of IA with SNP in SOX17 on chromosome 8q (rs1072737; P=8.7×10(-5)). 22961961

2012
dbSNP: rs6842241
rs6842241
EDNRA
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		C 0.810 GeneticVariation GWASDB We identified an SNP, rs6842241, near EDNRA at chromosome 4q31.22 (combined P-value = 9.58 × 10(-9); odds ratio = 1.25), which was found to be significantly associated with IA. 22286173

2012
dbSNP: rs11661542
rs11661542
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		C 0.800 GeneticVariation GWASDB Genome-wide association study of intracranial aneurysm identifies three new risk loci. 20364137

2010
dbSNP: rs12413409
rs12413409
CNNM2
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		G 0.800 GeneticVariation GWASDB Genome-wide association study of intracranial aneurysm identifies three new risk loci. 20364137

2010
dbSNP: rs1504749
rs1504749
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		C 0.800 GeneticVariation GWASDB Genome-wide association study of intracranial aneurysm identifies three new risk loci. 20364137

2010
dbSNP: rs9315204
rs9315204
STARD13
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		T 0.800 GeneticVariation GWASDB Genome-wide association study of intracranial aneurysm identifies three new risk loci. 20364137

2010
dbSNP: rs9864101
rs9864101
IQSEC1
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		0.710 GeneticVariation GWASDB Consequently, five SNPs (P=1.31 × 10(-5) for rs1930095 of intergenic region; P=1.32 × 10(-5) for rs4628172 of TMEM195; P=2.78 × 10(-5) for rs7781293 of TMEM195; P=4.93 × 10(-5) for rs7550260 of ARHGEF11; and P=3.63 × 10(-5) for rs9864101 of IQSEC1) with probabilities of being false positives <0.5 were associated with IA in Japanese population, and the susceptibility genes could have a role in actin remodeling in the ELN/LIMK pathway. 20613766

2010
dbSNP: rs11662668
rs11662668
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		0.700 GeneticVariation GWASDB Genome-wide association study of intracranial aneurysm identifies three new risk loci. 20364137

2010
dbSNP: rs12411886
rs12411886
CNNM2
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		0.700 GeneticVariation GWASDB Genome-wide association study of intracranial aneurysm identifies three new risk loci. 20364137

2010
dbSNP: rs1980781
rs1980781
STARD13
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		0.700 GeneticVariation GWASDB Genome-wide association study of intracranial aneurysm identifies three new risk loci. 20364137

2010
dbSNP: rs2383207
rs2383207
CDKN2B-AS1
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		0.700 GeneticVariation GWASDB Genome-wide association study of intracranial aneurysm identifies three new risk loci. 20364137

2010
dbSNP: rs3742321
rs3742321
STARD13
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		0.700 GeneticVariation GWASDB Genome-wide association study of intracranial aneurysm identifies three new risk loci. 20364137

2010
dbSNP: rs383730
rs383730
LOC107985412
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		0.700 GeneticVariation GWASDB Genome-wide association study of intracranial aneurysm identifies three new risk loci. 20364137

2010
dbSNP: rs4800418
rs4800418
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm 		0.700 GeneticVariation GWASDB Genome-wide association study of intracranial aneurysm identifies three new risk loci. 20364137

2010