rs1251794140
|
|
Encephalomyelitis
|
|
0.020 |
GeneticVariation
|
BEFREE |
Specifically, substituting proline at position 42 with serine in human MOG (as in rat MOG) eliminates the B cell requirement for EAE.
|
16172404 |
2005 |
rs1251794140
|
|
Encephalomyelitis
|
|
0.020 |
GeneticVariation
|
BEFREE |
We found that mMOG-35-55 peptide was strongly immunogenic and induced moderately severe chronic experimental autoimmune encephalomyelitis (EAE) with white matter lesions after a single injection in Freund's complete adjuvant followed by pertussis toxin. hMOG-35-55 peptide,which differs from mMOG-35-55 peptide by a proline for serine substitution at position 42, was also immunogenic, but not encephalitogenic, and was only partially cross-reactive with mMOG-35-55.
|
15114658 |
2004 |
rs182420962
|
|
Encephalomyelitis
|
|
0.020 |
GeneticVariation
|
BEFREE |
Specifically, substituting proline at position 42 with serine in human MOG (as in rat MOG) eliminates the B cell requirement for EAE.
|
16172404 |
2005 |
rs182420962
|
|
Encephalomyelitis
|
|
0.020 |
GeneticVariation
|
BEFREE |
We found that mMOG-35-55 peptide was strongly immunogenic and induced moderately severe chronic experimental autoimmune encephalomyelitis (EAE) with white matter lesions after a single injection in Freund's complete adjuvant followed by pertussis toxin. hMOG-35-55 peptide,which differs from mMOG-35-55 peptide by a proline for serine substitution at position 42, was also immunogenic, but not encephalitogenic, and was only partially cross-reactive with mMOG-35-55.
|
15114658 |
2004 |
rs1136758
|
|
Encephalomyelitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
We found that mMOG-35-55 peptide was strongly immunogenic and induced moderately severe chronic experimental autoimmune encephalomyelitis (EAE) with white matter lesions after a single injection in Freund's complete adjuvant followed by pertussis toxin. hMOG-35-55 peptide,which differs from mMOG-35-55 peptide by a proline for serine substitution at position 42, was also immunogenic, but not encephalitogenic, and was only partially cross-reactive with mMOG-35-55.
|
15114658 |
2004 |
rs1194494874
|
|
Encephalomyelitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
We found that mMOG-35-55 peptide was strongly immunogenic and induced moderately severe chronic experimental autoimmune encephalomyelitis (EAE) with white matter lesions after a single injection in Freund's complete adjuvant followed by pertussis toxin. hMOG-35-55 peptide,which differs from mMOG-35-55 peptide by a proline for serine substitution at position 42, was also immunogenic, but not encephalitogenic, and was only partially cross-reactive with mMOG-35-55.
|
15114658 |
2004 |
rs1418474769
|
|
Encephalomyelitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
A novel start codon GJB1 mutation (p.Met1Ile) has been found in a CMT1X patient presenting with recurrent episodes of transient encephalomyelitis without apparent signs of peripheral neuropathy.
|
25771809 |
2015 |
rs368311455
|
|
Encephalomyelitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results suggest that, lipids metabolism play an important role in EAE, as shown by the higher severity of disease progression in both WT EAE and WT EAF HFD-fed mice in contrast to their counterpart Cpt1a P479L mutant mice.
|
31527712 |
2019 |
rs80356779
|
|
Encephalomyelitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results suggest that, lipids metabolism play an important role in EAE, as shown by the higher severity of disease progression in both WT EAE and WT EAF HFD-fed mice in contrast to their counterpart Cpt1a P479L mutant mice.
|
31527712 |
2019 |