|
rs6547741
|
|
Malignant neoplasm of mouth
|
G |
0.710 |
GeneticVariation
|
GWASCAT |
Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L).
|
27749845 |
2016 |
|
rs6547741
|
|
Malignant neoplasm of mouth
|
|
0.710 |
GeneticVariation
|
BEFREE |
Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L).
|
27749845 |
2016 |
|
rs10462706
|
|
Malignant neoplasm of mouth
|
C |
0.700 |
GeneticVariation
|
GWASCAT |
Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L).
|
27749845 |
2016 |
|
rs10851478
|
|
Malignant neoplasm of mouth
|
G |
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
|
27749845 |
2016 |
|
rs1229984
|
|
Malignant neoplasm of mouth
|
G |
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
|
27749845 |
2016 |
|
rs1453414
|
|
Malignant neoplasm of mouth
|
C |
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
|
27749845 |
2016 |
|
rs1800628
|
|
Malignant neoplasm of mouth
|
A |
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
|
27749845 |
2016 |
|
rs2398180
|
|
Malignant neoplasm of mouth
|
T |
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
|
27749845 |
2016 |
|
rs3129780
|
|
Malignant neoplasm of mouth
|
A |
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
|
27749845 |
2016 |
|
rs3828805
|
|
Malignant neoplasm of mouth
|
C |
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
|
27749845 |
2016 |
|
rs77452476
|
|
Malignant neoplasm of mouth
|
C |
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
|
27749845 |
2016 |
|
rs79767424
|
|
Malignant neoplasm of mouth
|
C |
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer.
|
27749845 |
2016 |
|
rs8181047
|
|
Malignant neoplasm of mouth
|
A |
0.700 |
GeneticVariation
|
GWASCAT |
Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L).
|
27749845 |
2016 |
|
rs928674
|
|
Malignant neoplasm of mouth
|
G |
0.700 |
GeneticVariation
|
GWASCAT |
Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L).
|
27749845 |
2016 |
|
rs1217691063
|
|
Malignant neoplasm of mouth
|
|
0.080 |
GeneticVariation
|
BEFREE |
Pooled results indicated that neither C677T</span> nor A1298C polymorphism was associated with oral cancer susceptibility.
|
28138253 |
2017 |
|
rs1217691063
|
|
Malignant neoplasm of mouth
|
|
0.080 |
GeneticVariation
|
BEFREE |
The goals of this study were to evaluate the association of three genotypic polymorphism (MTHFR C677T, MTHFR A1298C and CBS 844ins68) and oral cancer risk in southeastern Brazilians and evaluate the interactions between polymorphisms and clinical histopathological parameters.
|
26749456 |
2016 |
|
rs1217691063
|
|
Malignant neoplasm of mouth
|
|
0.080 |
GeneticVariation
|
BEFREE |
Among these 14 variants, 9 variants were reported to be significantly associated with the risk of oral cancer (CYP1A1-MspI, CYP2E1-RsaI/PstI, MTHFR-C677T, p73-G4C14-to-A4T14, XRCC1-Arg194Trp, CYP1A1-Ile462Val, GSTM1-±, and NAT2 slow vs rapid).
|
24102947 |
2014 |
|
rs1217691063
|
|
Malignant neoplasm of mouth
|
|
0.080 |
GeneticVariation
|
BEFREE |
These results suggest that MTHFR C677T polymorphism may play a role in oral cancer carcinogenesis in Asian population and heavy drinkers.
|
24488626 |
2014 |
|
rs1217691063
|
|
Malignant neoplasm of mouth
|
|
0.080 |
GeneticVariation
|
BEFREE |
Here we observed MTHFR C677T to influence oral cancer susceptibility, while A1298C polymorphism associated with patient prognosis.
|
20923444 |
2011 |
|
rs1217691063
|
|
Malignant neoplasm of mouth
|
|
0.080 |
GeneticVariation
|
BEFREE |
Those patients with MTHFR C677T CT and TT genotypes also had a lower risk of oral cancer metastasis.
|
21737671 |
2011 |
|
rs1217691063
|
|
Malignant neoplasm of mouth
|
|
0.080 |
GeneticVariation
|
BEFREE |
Interaction between the MTHFR C677T polymorphism and alcohol--impact on oral cancer risk and multiple DNA methylation of tumor-related genes.
|
20940365 |
2011 |
|
rs1217691063
|
|
Malignant neoplasm of mouth
|
|
0.080 |
GeneticVariation
|
BEFREE |
Folate intake, serum homocysteine and methylenetetrahydrofolate reductase (MTHFR) C677T genotype are not associated with oral cancer risk in Puerto Rico.
|
11925474 |
2002 |
|
rs1799782
|
|
Malignant neoplasm of mouth
|
|
0.080 |
GeneticVariation
|
BEFREE |
The best two-factor based G×G interaction of ora</span>l cancer included the XRCC1 rs1799782 and XRCC2 rs2040639 [OR=3.13, 95% CI=1.66-6.13].
|
25831063 |
2015 |
|
rs1799782
|
|
Malignant neoplasm of mouth
|
|
0.080 |
GeneticVariation
|
BEFREE |
The meta-analysis results suggest that the XRCC1 Arg399Gln and Arg280His polymorphisms are probably not associated with the risk of HNC, but the XRCC1 Arg194Trp polymorphism was associated with increased risk of HNC in the subgroup analysis of studies adjusted for smoking and alcohol and with increased risk of oral cancer in the stratified analyses based on cancer site.
|
24497981 |
2014 |
|
rs1799782
|
|
Malignant neoplasm of mouth
|
|
0.080 |
GeneticVariation
|
BEFREE |
Among these 14 variants, 9 variants were reported to be significantly associated with the risk of oral cancer (CYP1A1-MspI, CYP2E1-RsaI/PstI, MTHFR-C677T, p73-G4C14-to-A4T14, XRCC1-Arg194Trp, CYP1A1-Ile462Val, GSTM1-±, and NAT2 slow vs rapid).
|
24102947 |
2014 |