DisGeNET - a database of gene-disease associations

Source: ALL

Gene: AGPAT1 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1061808

PPT2 ; AGPAT1 ; EGFL8 ; PPT2-EGFL8

CUI:	C0202177
Disease:	Phospholipid measurement

Phospholipid measurement

0.800

GeneticVariation

GWASDB

Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.

22359512

2012

dbSNP:

rs1061808

PPT2 ; AGPAT1 ; EGFL8 ; PPT2-EGFL8

CUI:	C0202177
Disease:	Phospholipid measurement

Phospholipid measurement

0.800

GeneticVariation

GWASCAT

Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.

22359512

2012

dbSNP:

rs1061808

PPT2 ; AGPAT1 ; EGFL8 ; PPT2-EGFL8

CUI:	C2985280
Disease:	Blood Protein Measurement

Blood Protein Measurement

0.700

GeneticVariation

GWASCAT

Genomic atlas of the human plasma proteome.

29875488

2018

dbSNP:

rs1269839

PPT2 ; AGPAT1 ; PPT2-EGFL8

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

21156761

2011

dbSNP:

rs3130284

AGPAT1

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

21156761

2011

dbSNP:

rs3130284

AGPAT1

CUI:	C0042900
Disease:	Vitiligo

Vitiligo

0.700

GeneticVariation

GWASDB

Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC.

20526339

2010

dbSNP:

rs3130348

AGPAT1

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

21156761

2011

dbSNP:

rs3130349

RNF5 ; AGPAT1 ; MIR6833

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

21156761

2011

dbSNP:

rs3131297

AGPAT1

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

21156761

2011

dbSNP:

rs3132965

RNF5 ; AGPAT1 ; MIR6833

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

21156761

2011

dbSNP:

rs3134943

RNF5 ; AGPAT1 ; MIR6833

CUI:	C0026769
Disease:	Multiple Sclerosis

Multiple Sclerosis

0.700

GeneticVariation

GWASDB

Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis.

20598377

2010

dbSNP:

rs3134943

RNF5 ; AGPAT1 ; MIR6833

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.

19503088

2009

dbSNP:

rs3134943

RNF5 ; AGPAT1 ; MIR6833

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.

17804836

2007

dbSNP:

rs3134943

RNF5 ; AGPAT1 ; MIR6833

CUI:	C0011854
Disease:	Diabetes Mellitus, Insulin-Dependent

Diabetes Mellitus, Insulin-Dependent

0.700

GeneticVariation

GWASDB

A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.

17632545

2007

dbSNP:

rs3134945

RNF5 ; AGPAT1 ; MIR6833

CUI:	C0024141
Disease:	Lupus Erythematosus, Systemic

Lupus Erythematosus, Systemic

0.700

GeneticVariation

GWASDB

GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.

24871463

2014

dbSNP:

rs3134945

RNF5 ; AGPAT1 ; MIR6833

CUI:	C0017665
Disease:	Membranous glomerulonephritis

Membranous glomerulonephritis

0.700

GeneticVariation

GWASCAT

Risk HLA-DQA1 and PLA(2)R1 alleles in idiopathic membranous nephropathy.

21323541

2011

dbSNP:

rs3134945

RNF5 ; AGPAT1 ; MIR6833

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

21156761

2011

dbSNP:

rs3134945

RNF5 ; AGPAT1 ; MIR6833

CUI:	C0042900
Disease:	Vitiligo

Vitiligo

0.700

GeneticVariation

GWASDB

Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC.

20526339

2010

dbSNP:

rs3134945

RNF5 ; AGPAT1 ; MIR6833

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.

19503088

2009

dbSNP:

rs3134945

RNF5 ; AGPAT1 ; MIR6833

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.

17804836

2007

dbSNP:

rs3134946

RNF5 ; AGPAT1 ; MIR6833

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

21156761

2011

dbSNP:

rs3134947

RNF5 ; AGPAT1

CUI:	C0003873
Disease:	Rheumatoid Arthritis

Rheumatoid Arthritis

0.700

GeneticVariation

GWASDB

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.

21156761

2011

dbSNP:

rs3134947

RNF5 ; AGPAT1

CUI:	C0042900
Disease:	Vitiligo

Vitiligo

0.700

GeneticVariation

GWASDB

Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC.

20526339

2010

dbSNP:

rs408359

AGPAT1

CUI:	C0011854
Disease:	Diabetes Mellitus, Insulin-Dependent

Diabetes Mellitus, Insulin-Dependent

0.700

GeneticVariation

GWASDB

A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.

17632545

2007

dbSNP:

rs17493811

RNF5 ; AGPAT1

CUI:	C0011854
Disease:	Diabetes Mellitus, Insulin-Dependent

Diabetes Mellitus, Insulin-Dependent

0.010

GeneticVariation

BEFREE

The rs2070600 and rs17493811 polymorphisms predicted increased risk of type 1 diabetes, whereas the rs9469089 SNP was related to decreased risk, on a high risk HLA background.

21298413

2011