|
rs671
|
|
Alcoholic Intoxication, Chronic
|
|
0.900 |
GeneticVariation
|
GWASDB |
When rs671 was considered as a candidate SNP in females, it explained 23.6% of the variation in flushing response, but alcohol consumption rates were too low among females-despite familial enrichment for AD-for an adequate test of association for either AD or maximum drinks.
|
24277619 |
2014 |
|
rs671
|
|
Coronary heart disease
|
A |
0.900 |
GeneticVariation
|
GWASDB |
Genome-wide association study of coronary artery disease in the Japanese.
|
21971053 |
2012 |
|
rs671
|
|
Esophageal Neoplasms
|
|
0.880 |
GeneticVariation
|
GWASDB |
Strong interaction between the effects of alcohol consumption and smoking on oesophageal squamous cell carcinoma among individuals with ADH1B and/or ALDH2 risk alleles.
|
20833657 |
2010 |
|
rs2238151
|
|
Cerebrovascular accident
|
T |
0.800 |
GeneticVariation
|
GWASDB |
Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies.
|
23041239 |
2012 |
|
rs671
|
|
Drinking behavior processes
|
|
0.800 |
GeneticVariation
|
GWASDB |
Moreover, we observed the association with drinking behavior for a functional variant in ALDH2 at 12q24 (rs671, P-discovery = 5.17 × 10(-35)).
|
23364009 |
2013 |
|
rs671
|
|
Alcohol consumption
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population.
|
23555315 |
2013 |
|
rs671
|
|
Drinking behavior processes
|
|
0.800 |
GeneticVariation
|
GWASDB |
A cluster of 12 SNPs on 12q24 were found to significantly (P<5×10(-8)) associate with drinking behavior in stage 1, among which rs671 (a Glu-to-Lys substitution at position 504) in the ALDH2 gene showed the strongest association (odds ratio (OR)=0.16, P=3.6×10(-211) in the joint analysis).
|
21372407 |
2011 |
|
rs671
|
|
Malignant neoplasm of esophagus
|
|
0.780 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.
|
21642993 |
2011 |
|
rs671
|
|
Malignant neoplasm of esophagus
|
A |
0.780 |
GeneticVariation
|
GWASDB |
Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.
|
19698717 |
2009 |
|
rs671
|
|
Hepatitis B
|
|
0.710 |
GeneticVariation
|
GWASDB |
A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.
|
21750111 |
2011 |
|
rs11066028
|
|
Corpuscular Hemoglobin Concentration Mean
|
|
0.700 |
GeneticVariation
|
GWASDB |
Seventy-five genetic loci influencing the human red blood cell.
|
23222517 |
2012 |
|
rs4646776
|
|
Drinking behavior processes
|
|
0.700 |
GeneticVariation
|
GWASDB |
Common variants at 12q24 are associated with drinking behavior in Han Chinese.
|
23364009 |
2013 |
|
rs4646776
|
|
Malignant neoplasm of esophagus
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.
|
21642993 |
2011 |
|
rs4648328
|
|
Corpuscular Hemoglobin Concentration Mean
|
|
0.700 |
GeneticVariation
|
GWASDB |
Seventy-five genetic loci influencing the human red blood cell.
|
23222517 |
2012 |
|
rs671
|
|
Finding of body mass index
|
G |
0.700 |
GeneticVariation
|
GWASDB |
Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.
|
24861553 |
2014 |
|
rs671
|
|
Body mass index procedure
|
G |
0.700 |
GeneticVariation
|
GWASDB |
The association of BMI with rs2237892, rs671 and rs12229654 was significantly stronger among men than among women.
|
24861553 |
2014 |
|
rs671
|
|
Nasopharyngeal carcinoma
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci.
|
20512145 |
2010 |