|
rs12153855
|
|
Age related macular degeneration
|
C |
0.820 |
GeneticVariation
|
GWASDB |
Using a replication sample of 1411 advanced AMD cases and 1431 examined controls, we confirmed a novel association between AMD and single-nucleotide polymorphisms on chromosome 6p21.3 at TNXB (tenascin XB)-FKBPL (FK506 binding protein like) [rs12153855/rs9391734; discovery P =4.3 × 10(-7), replication P =3.0 × 10(-4), combined P =1.3 × 10(-9), odds ratio (OR) = 1.4, 95% confidence interval (CI) = 1.3-1.6] and the neighbouring gene NOTCH4 (Notch 4) (rs2071277; discovery P =3.2 × 10(-8), replication P =3.8 × 10(-5), combined P =2.0 × 10(-11), OR = 1.3, 95% CI = 1.2-1.4).
|
22694956 |
2012 |
|
rs1150754
|
|
Lupus Erythematosus, Systemic
|
A |
0.810 |
GeneticVariation
|
GWASDB |
Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.
|
21408207 |
2011 |
|
rs17207986
|
|
Ulcerative Colitis
|
|
0.810 |
GeneticVariation
|
GWASDB |
Comparison of the MR-UC subjects with healthy controls confirmed the contribution of the major histocompatibility complex to severe UC (peak association: rs17207986, P = 1.4 × 10(-16)) and provided genome-wide suggestive association at the TNFSF15 (TL1A) locus (peak association: rs11554257, P = 1.4 × 10(-6)).
|
20848476 |
2010 |
|
rs12153855
|
|
Dermatitis, Atopic
|
T |
0.800 |
GeneticVariation
|
GWASDB |
A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.
|
23886662 |
2013 |
|
rs2857009
|
|
C4 complement assay (procedure)
|
G |
0.800 |
GeneticVariation
|
GWASDB |
Genome-wide association study for serum complement C3 and C4 levels in healthy Chinese subjects.
|
23028341 |
2012 |
|
rs3130342
|
|
Lupus Erythematosus, Systemic
|
|
0.710 |
GeneticVariation
|
GWASDB |
Stratified analysis also revealed that the association of SNP rs3130342 with SLE was independent of the HLA-DRB1*1501 allele that has been shown to be associated with SLE.
|
18058064 |
2008 |
|
rs1150752
|
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
|
rs1150752
|
|
Adenocarcinoma of lung (disorder)
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma.
|
19836008 |
2009 |
|
rs1150752
|
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
|
17632545 |
2007 |
|
rs1150753
|
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis.
|
21156761 |
2011 |
|
rs1150754
|
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
|
17632545 |
2007 |
|
rs12153855
|
|
Systemic Scleroderma
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus.
|
20383147 |
2010 |
|
rs12153855
|
|
ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO
|
|
0.700 |
GeneticVariation
|
GWASDB |
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
|
21051598 |
2010 |
|
rs12153855
|
|
AIDS, PROGRESSION TO
|
|
0.700 |
GeneticVariation
|
GWASDB |
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
|
21051598 |
2010 |
|
rs12153855
|
|
Vitiligo
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC.
|
20526339 |
2010 |
|
rs12153855
|
|
HIV-1, RESISTANCE TO
|
|
0.700 |
GeneticVariation
|
GWASDB |
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
|
21051598 |
2010 |
|
rs12153855
|
|
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO
|
|
0.700 |
GeneticVariation
|
GWASDB |
The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.
|
21051598 |
2010 |
|
rs12153855
|
|
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO
|
|
0.700 |
GeneticVariation
|
GWASDB |
Common genetic variation and the control of HIV-1 in humans.
|
20041166 |
2009 |
|
rs12153855
|
|
ACQUIRED IMMUNODEFICIENCY SYNDROME, PROGRESSION TO
|
|
0.700 |
GeneticVariation
|
GWASDB |
Common genetic variation and the control of HIV-1 in humans.
|
20041166 |
2009 |
|
rs12153855
|
|
AIDS, PROGRESSION TO
|
|
0.700 |
GeneticVariation
|
GWASDB |
Common genetic variation and the control of HIV-1 in humans.
|
20041166 |
2009 |
|
rs12153855
|
|
HIV-1, RESISTANCE TO
|
|
0.700 |
GeneticVariation
|
GWASDB |
Common genetic variation and the control of HIV-1 in humans.
|
20041166 |
2009 |
|
rs12153855
|
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation
|
GWASDB |
REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.
|
19503088 |
2009 |
|
rs12153855
|
|
Diabetes Mellitus, Insulin-Dependent
|
|
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
|
17632545 |
2007 |
|
rs12153855
|
|
Rheumatoid Arthritis
|
|
0.700 |
GeneticVariation
|
GWASDB |
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.
|
17804836 |
2007 |
|
rs12198173
|
|
Dermatitis, Atopic
|
G |
0.700 |
GeneticVariation
|
GWASDB |
A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.
|
23886662 |
2013 |