|
rs138551969
|
|
Creatinine measurement, serum (procedure)
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.
|
29124443 |
2018 |
|
rs138551969
|
|
Glomerular Filtration Rate
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.
|
29124443 |
2018 |
|
rs138551969
|
|
Hyperuricemia
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.
|
29124443 |
2018 |
|
rs138551969
|
|
Uric acid measurement (procedure)
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Identification of CDC42BPG as a novel susceptibility locus for hyperuricemia in a Japanese population.
|
29124443 |
2018 |
|
rs2010963
|
|
MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 1(finding)
|
G |
0.700 |
SusceptibilityMutation
|
CLINVAR |
|
|
|
|
rs3025021
|
|
Interleukin 10 Measurement
|
C |
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.
|
27989323 |
2017 |
|
rs833070
|
|
Red Blood Cell Count measurement
|
C |
0.700 |
GeneticVariation
|
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
rs833070
|
|
Hematocrit procedure
|
C |
0.700 |
GeneticVariation
|
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
rs833070
|
|
Hemoglobin measurement
|
C |
0.700 |
GeneticVariation
|
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
rs2010963
|
|
Coronary Artery Disease
|
|
0.060 |
GeneticVariation
|
BEFREE |
In summary, we concluded that the VEGF gene polymorphisms rs699947, rs2010963, and rs3025039 are correlated with an elevated CAD risk.
|
29973139 |
2018 |
|
rs2010963
|
|
Coronary Artery Disease
|
|
0.060 |
GeneticVariation
|
BEFREE |
Vascular endothelial growth factor rs20</span>10963 polymorphism may be associated with the presence of CAD and its long-term survival, but not with its severity.
|
27704620 |
2017 |
|
rs2010963
|
|
Coronary Artery Disease
|
|
0.060 |
GeneticVariation
|
BEFREE |
Our results indicated that ACE(rs4646994)-D allele alone and in the presence of VEGF(rs2010963)-G allele can be an important independent risk factor for susceptibility of CAD in T2DM patients even after correcting for conventional risk factors in a population of Iran.
|
24505095 |
2015 |
|
rs2010963
|
|
Coronary Artery Disease
|
|
0.060 |
GeneticVariation
|
BEFREE |
The possible association of rs699947 and rs2010963 with CAD risks warrant confirmation in independent case-control studies and may be informative for future investigations on the pathogenesis of CAD.
|
23545315 |
2013 |
|
rs2010963
|
|
Coronary Artery Disease
|
|
0.060 |
GeneticVariation
|
BEFREE |
Logistic regression analyses revealed that the VEGFA rs699947 C/A, VEGFA rs2010963 G/C, and VEGFA rs3025039 C/T polymorphisms were not associated with a risk of CAD.
|
23880405 |
2013 |
|
rs2010963
|
|
Coronary Artery Disease
|
|
0.060 |
GeneticVariation
|
BEFREE |
This study tested the association between functional VEGF +405 C>G (rs2010963), -2578C>A (rs699947) polymorphisms, and coronary collaterals in patients with coronary artery disease (CAD).
|
20621071 |
2010 |
|
rs699947
|
|
Diabetic Retinopathy
|
|
0.060 |
GeneticVariation
|
BEFREE |
The VEGF gene SNPs analyzed with regard to DR susceptibility were rs2010963 (G > C), rs833061 (T > C), rs699947 (C > A), rs3025039 (C > T) and rs1570360 (G > A).
|
27613596 |
2017 |
|
rs699947
|
|
Diabetic Retinopathy
|
|
0.060 |
GeneticVariation
|
BEFREE |
After adjustment for covariates, significant association of DR remained with the homozygous genotype of the minor allele for the SNPs rs699947 (odds ratio [OR] = 3.54, 95% confidence interval [CI]: 1.12-11.19), rs833061 (OR = 3.72, 95% CI: 1.17-11.85), rs13207351 (OR = 3.76, 95% CI: 1.21-11.71), and rs2146323 (OR = 2.8, 95% CI: 1.46-5.37) in the VEGF gene as well as the SNP rs2071559 (OR = 1.62, 95% CI: 1.08-2.41) in the KDR gene.
|
24623964 |
2014 |
|
rs699947
|
|
Diabetic Retinopathy
|
|
0.060 |
GeneticVariation
|
BEFREE |
No evidence of association was observed between -2578 A/C (rs699947), +405C/G (rs2010963), +936C/T (rs3025039), and DR risk under stringent Bonferroni's correction.
|
24534217 |
2014 |
|
rs699947
|
|
Diabetic Retinopathy
|
|
0.060 |
GeneticVariation
|
BEFREE |
Our meta-analysis confirmed the significant association between rs699947 polymorphism and DR after exclusion of outliers, and rs2010963 polymorphism might be not associated with DR.
|
24131746 |
2013 |
|
rs699947
|
|
Diabetic Retinopathy
|
|
0.060 |
GeneticVariation
|
BEFREE |
After adjusting for covariates, a significant association of DR was observed with the homozygous genotype of the minor allele for promoter SNPs rs699947 (odds ratio (OR)=3.54, 95% confidence interval (CI): 1.12-11.19), rs833061 (OR=3.72, 95% CI: 1.17-11.85) and rs13207351 (OR=3.76, 95% CI: 1.21-11.71).
|
22162628 |
2011 |
|
rs699947
|
|
Diabetic Retinopathy
|
|
0.060 |
GeneticVariation
|
BEFREE |
We found a significant association between the A allele at rs699947 with DR (odds ratio = 1.84 (95% confidence interval = 1.28-2.66); P = 0.001 vs. noDR).
|
20444917 |
2010 |
|
rs833061
|
|
Age related macular degeneration
|
|
0.060 |
GeneticVariation
|
BEFREE |
However, weak correlations between 10 SNPs (CFH rs1329428 TT genotype, CFH rs3753394 CC genotype and T allele, CFH rs1410996 AA genotype, CFH rs800292 AA genotype, CFH rs800292 A allele, VEGF rs833061 TT genotype and C allele, VEGF rs2010963 CG genotype, VEGFR2 rs1531289 TT genotype, ARMS2 rs10490924 TT genotype, KCTD10 rs238104 GC genotype, rs1531289 T allele and ARMS2 rs10490924 T allele) and AMD were shown.
|
30696427 |
2019 |
|
rs833061
|
|
Age related macular degeneration
|
|
0.060 |
GeneticVariation
|
BEFREE |
Significant associations with AMD risk were showed for rs833061, rs1413711, and rs3025039 polymorphisms but not for rs2010963.
|
27999450 |
2016 |
|
rs833061
|
|
Age related macular degeneration
|
|
0.060 |
GeneticVariation
|
BEFREE |
The meta-analysis results based on nine case-control studies with 2427 cases and 2037 controls showed that rs833061 had protective effects on AMD risk (TT vs. CT+CC: OR=0.58, 95% CI=0.41-0.81), whereas rs1413711 (TT vs. CT+CC: OR=1.46, 95% CI=1.10-1.93) and rs3025039 (TT vs. CC: OR=1.87, 95% CI=1.15-3.02; TT vs. CT+CC: OR=2.09, 95% CI=1.30-3.37) represented as risk factors for AMD.
|
24689893 |
2014 |
|
rs833061
|
|
Age related macular degeneration
|
|
0.060 |
GeneticVariation
|
BEFREE |
Our study shows that VEGFA rs699947 and rs833061 and VEGFR2 rs2071559 polymorphisms do not modify the risk of suffering AMD in a Spanish population.
|
23971975 |
2013 |