|
rs3731217
|
|
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia.
|
29632299 |
2018 |
|
rs3731217
|
|
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype.
|
23996088 |
2013 |
|
rs3731217
|
|
Childhood Acute Lymphoblastic Leukemia
|
|
0.050 |
GeneticVariation
|
BEFREE |
Here, we conducted a systematic review and meta-analysis to re-evaluate the association of both SNPs (rs3731217 and rs3731249) with ALL susceptibility by gathering the data from 24 independent studies, totally containing 7922 cases/21503 controls for rs3731217 and 6295 cases/24191 controls for rs3731249.
|
29654170 |
2018 |
|
rs3731217
|
|
Childhood Acute Lymphoblastic Leukemia
|
|
0.050 |
GeneticVariation
|
BEFREE |
No associations were found between the IKZF1 SNPs (rs11978267; rs7789635), DDC SNPs (rs3779084; rs880028; rs7809758), CDKN2A SNP (rs3731217), the CEBPE SNPs (rs2239633; rs12434881) and LMO1 SNPs (rs442264; rs3794012; rs4237770) with ALL in Yemeni children.
|
28768142 |
2017 |
|
rs3731217
|
|
Childhood Acute Lymphoblastic Leukemia
|
|
0.050 |
GeneticVariation
|
BEFREE |
These SNPs are located at CDKN2A (rs3731217) and IKZF1 (rs4132601), genes frequently lost in ALL, and at CEBPE (rs2239633), ARID5B (rs7089424), PIP4K2A (rs10764338), and GATA3 (rs3824662), genes located on chromosomes gained in high-hyperdiploid ALL.
|
26575185 |
2015 |
|
rs3731217
|
|
Childhood Acute Lymphoblastic Leukemia
|
|
0.050 |
GeneticVariation
|
BEFREE |
To explore the impact of these variants on ALL risk in the Thai population, we genotyped 190 cases of ALL and 182 controls for SNPs rs4132601 (7p12.2), rs3731217 (9p21.3), rs7089424 and rs10821938 (10q21.2), and rs2239633 (14q11.2).
|
20919861 |
2010 |
|
rs3731217
|
|
Childhood Acute Lymphoblastic Leukemia
|
|
0.050 |
GeneticVariation
|
BEFREE |
Using data from a genome-wide association study of 907 individuals with childhood acute lymphoblastic leukemia (cases) and 2,398 controls and with validation in samples totaling 2,386 cases and 2,419 controls, we have shown that common variation at 9p21.3 (rs3731217, intron 1 of CDKN2A) influences acute lymphoblastic leukemia risk (odds ratio = 0.71, P = 3.01 x 10(-11)), irrespective of cell lineage.
|
20453839 |
2010 |
|
rs3731217
|
|
Acute lymphocytic leukemia
|
|
0.030 |
GeneticVariation
|
BEFREE |
Here, we conducted a systematic review and meta-analysis to re-evaluate the association of both SNPs (rs3731217 and rs3731249) with ALL susceptibility by gathering the data from 24 independent studies, totally containing 7922 cases/21503 controls for rs3731217 and 6295 cases/24191 controls for rs3731249.
|
29654170 |
2018 |
|
rs3731217
|
|
Acute lymphocytic leukemia
|
|
0.030 |
GeneticVariation
|
BEFREE |
No associations were found between the IKZF1 SNPs (rs11978267; rs7789635), DDC SNPs (rs3779084; rs880028; rs7809758), CDKN2A SNP (rs3731217), the CEBPE SNPs (rs2239633; rs12434881) and LMO1 SNPs (rs442264; rs3794012; rs4237770) with ALL in Yemeni children.
|
28768142 |
2017 |
|
rs3731217
|
|
Acute lymphocytic leukemia
|
|
0.030 |
GeneticVariation
|
BEFREE |
Using data from a genome-wide association study of 907 individuals with childhood acute lymphoblastic leukemia (cases) and 2,398 controls and with validation in samples totaling 2,386 cases and 2,419 controls, we have shown that common variation at 9p21.3 (rs3731217, intron 1 of CDKN2A) influences acute lymphoblastic leukemia risk (odds ratio = 0.71, P = 3.01 x 10(-11)), irrespective of cell lineage.
|
20453839 |
2010 |
|
rs3731217
|
|
Adult Acute Lymphocytic Leukemia
|
|
0.020 |
GeneticVariation
|
BEFREE |
Here, we conducted a systematic review and meta-analysis to re-evaluate the association of both SNPs (rs3731217 and rs3731249) with ALL susceptibility by gathering the data from 24 independent studies, totally containing 7922 cases/21503 controls for rs3731217 and 6295 cases/24191 controls for rs3731249.
|
29654170 |
2018 |
|
rs3731217
|
|
Adult Acute Lymphocytic Leukemia
|
|
0.020 |
GeneticVariation
|
BEFREE |
No associations were found between the IKZF1 SNPs (rs11978267; rs7789635), DDC SNPs (rs3779084; rs880028; rs7809758), CDKN2A SNP (rs3731217), the CEBPE SNPs (rs2239633; rs12434881) and LMO1 SNPs (rs442264; rs3794012; rs4237770) with ALL in Yemeni children.
|
28768142 |
2017 |
|
rs3731217
|
|
Hyperdiploid B Acute Lymphoblastic Leukemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
These SNPs are located at CDKN2A (rs3731217) and IKZF1 (rs4132601), genes frequently lost in ALL, and at CEBPE (rs2239633), ARID5B (rs7089424), PIP4K2A (rs10764338), and GATA3 (rs3824662), genes located on chromosomes gained in high-hyperdiploid ALL.
|
26575185 |
2015 |
|
rs3731217
|
|
Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
We determined tumor HPV16 status and expression of p14/p53 and genotyped p14 (ARF) -rs3731217 and -rs3088440 polymorphisms in 552 incident SCCOP patients.
|
24104554 |
2014 |
|
rs3731217
|
|
Squamous cell carcinoma of oropharynx
|
|
0.010 |
GeneticVariation
|
BEFREE |
Multivariable analysis found that patients with p14 (ARF) -rs3731217 TT genotype had an ~7-, 11- and 3-fold increased risk for death overall, death due to SCCOP and recurrence than those with TG/GG variant genotypes, respectively.
|
24104554 |
2014 |
|
rs3731217
|
|
Differentiated Thyroid Gland Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
MDM2-rs2279744 and p14(ARF)-rs3731217 were associated with a significantly increased risk of DTC (MDM2-rs2279744: TT versus TG/GG; OR, 1.5; 95% CI, 1.1-2.0; p14(ARF)-rs3731217: TG/GG versus TT; OR, 1.7; 95% CI, 1.2-2.3).
|
23218882 |
2013 |
|
rs3731217
|
|
SCAPULOPERONEAL MYOPATHY, X-LINKED DOMINANT
|
|
0.010 |
GeneticVariation
|
BEFREE |
Compared with the p14(ARF) thymine-thymine (TT) and guanine-guanine (GG) genotypes, the variant genotypes of p14(ARF) TG/GG and guanine-adenine (GA)/AA were associated with a significantly moderately increased risk of developing an SPM (p14(ARF) rs3731217: adjusted hazard ratio [aHR], 1.48; 95% confidence interval [CI], 1.00-2.19; p14(ARF) rs3088440: aHR, 1.61; 95% CI, 1.07-2.43).
|
21381012 |
2011 |
|
rs3731217
|
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Using data from a genome-wide association study of 907 individuals with childhood acute lymphoblastic leukemia (cases) and 2,398 controls and with validation in samples totaling 2,386 cases and 2,419 controls, we have shown that common variation at 9p21.3 (rs3731217, intron 1 of CDKN2A) influences acute lymphoblastic leukemia risk (odds ratio = 0.71, P = 3.01 x 10(-11)), irrespective of cell lineage.
|
20453839 |
2010 |