Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4968451
rs4968451
CUI: C0278877
Disease: Adult Meningioma
Adult Meningioma
0.020 GeneticVariation BEFREE The polymorphisms rs4968451T>G in BRIP1 were significantly associated with the risk of meningioma (TT vs. TG vs. GG additive, P = 0.005; TT+TG vs. GG dominant, P = 0.015; TT/GT+GG recessive, P = 0.034). 29581016

2018

dbSNP: rs4968451
rs4968451
CUI: C0025286
Disease: Meningioma
Meningioma
0.020 GeneticVariation BEFREE The polymorphisms rs4968451T>G in BRIP1 were significantly associated with the risk of meningioma (TT vs. TG vs. GG additive, P = 0.005; TT+TG vs. GG dominant, P = 0.015; TT/GT+GG recessive, P = 0.034). 29581016

2018

dbSNP: rs4968451
rs4968451
Meningioma, benign, no ICD-O subtype
0.020 GeneticVariation BEFREE The polymorphisms rs4968451T>G in BRIP1 were significantly associated with the risk of meningioma (TT vs. TG vs. GG additive, P = 0.005; TT+TG vs. GG dominant, P = 0.015; TT/GT+GG recessive, P = 0.034). 29581016

2018

dbSNP: rs4968451
rs4968451
Meningioma, benign, no ICD-O subtype
0.020 GeneticVariation BEFREE We have identified a novel association between rs4968451 and meningioma risk. 18270339

2008

dbSNP: rs4968451
rs4968451
CUI: C0278877
Disease: Adult Meningioma
Adult Meningioma
0.020 GeneticVariation BEFREE We have identified a novel association between rs4968451 and meningioma risk. 18270339

2008

dbSNP: rs4968451
rs4968451
CUI: C0025286
Disease: Meningioma
Meningioma
0.020 GeneticVariation BEFREE We have identified a novel association between rs4968451 and meningioma risk. 18270339

2008

dbSNP: rs4968451
rs4968451
CUI: C1512260
Disease: Grade I Meningioma
Grade I Meningioma
0.010 GeneticVariation BEFREE BRIP1 rs4968451T>G was associated with markedly grade I meningioma risk (TT+TG vs. GG dominant, P = 0.008; TT/GT+GG recessive, P = 0.020). 29581016

2018

dbSNP: rs4968451
rs4968451
CUI: C2347751
Disease: Adult Grade I Meningioma
Adult Grade I Meningioma
0.010 GeneticVariation BEFREE BRIP1 rs4968451T>G was associated with markedly grade I meningioma risk (TT+TG vs. GG dominant, P = 0.008; TT/GT+GG recessive, P = 0.020). 29581016

2018

dbSNP: rs4968451
rs4968451
CUI: C2347760
Disease: Childhood Grade I Meningioma
Childhood Grade I Meningioma
0.010 GeneticVariation BEFREE BRIP1 rs4968451T>G was associated with markedly grade I meningioma risk (TT+TG vs. GG dominant, P = 0.008; TT/GT+GG recessive, P = 0.020). 29581016

2018

dbSNP: rs4968451
rs4968451
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.010 GeneticVariation BEFREE Through genotype-phenotype analysis, the genotype of BRIP1 rs4968451T>G was also strongly associated with tumor-related phenotypes, including the tumor grade and tumor subtypes. 29581016

2018

dbSNP: rs4968451
rs4968451
CUI: C0334611
Disease: Transitional Meningioma
Transitional Meningioma
0.010 GeneticVariation BEFREE In addition, BRIP1 rs4968451T>G was associated with markedly meningothelial and transitional meningioma risk. 29581016

2018

dbSNP: rs4968451
rs4968451
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma
0.010 GeneticVariation BEFREE The results showed that rs16945692 (intron 1), rs4968451 (intron 4), rs4986764 (exon 18) and rs7213430 (3'UTR) were significantly associated with cervical cancer (P<0.05). 23644138

2013

dbSNP: rs4968451
rs4968451
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.010 GeneticVariation BEFREE The results showed that rs16945692 (intron 1), rs4968451 (intron 4), rs4986764 (exon 18) and rs7213430 (3'UTR) were significantly associated with cervical cancer (P<0.05). 23644138

2013

dbSNP: rs4968451
rs4968451
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.010 GeneticVariation BEFREE The results showed that rs16945692 (intron 1), rs4968451 (intron 4), rs4986764 (exon 18) and rs7213430 (3'UTR) were significantly associated with cervical cancer (P<0.05). 23644138

2013

dbSNP: rs4968451
rs4968451
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.010 GeneticVariation BEFREE The SNP rs4968451, which maps to intron 4 of the gene that encodes breast cancer susceptibility gene 1-interacting protein 1, was consistently associated with an increased risk of developing meningioma. 18270339

2008

dbSNP: rs4968451
rs4968451
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.010 GeneticVariation BEFREE The SNP rs4968451, which maps to intron 4 of the gene that encodes breast cancer susceptibility gene 1-interacting protein 1, was consistently associated with an increased risk of developing meningioma. 18270339

2008