Source: CURATED

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs8042374
rs8042374
CHRNA3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.710 GeneticVariation GWASDB Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. 22899653

2012
dbSNP: rs8042374
rs8042374
CHRNA3
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		0.710 GeneticVariation GWASDB A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. 19836008

2009
dbSNP: rs8042374
rs8042374
CHRNA3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.710 GeneticVariation GWASDB Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study. 19654303

2009
dbSNP: rs8042374
rs8042374
CHRNA3
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.710 GeneticVariation GWASCAT Common 5p15.33 and 6p21.33 variants influence lung cancer risk. 18978787

2008
dbSNP: rs8042374
rs8042374
CHRNA3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.710 GeneticVariation GWASDB Common 5p15.33 and 6p21.33 variants influence lung cancer risk. 18978787

2008
dbSNP: rs8042374
rs8042374
CHRNA3
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		A 0.700 GeneticVariation GWASCAT Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia. 28540026

2017
dbSNP: rs8042374
rs8042374
CHRNA3
CUI: C0008074
Disease: Child Development Disorders, Pervasive
Child Development Disorders, Pervasive 		A 0.700 GeneticVariation GWASCAT Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia. 28540026

2017
dbSNP: rs8042374
rs8042374
CHRNA3
CUI: C3548479
Disease: response to bronchodilator
response to bronchodilator 		A 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245

2015
dbSNP: rs8042374
rs8042374
CHRNA3
CUI: C0016529
Disease: Forced expiratory volume function
Forced expiratory volume function 		A 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245

2015
dbSNP: rs8042374
rs8042374
CHRNA3
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		A 0.700 GeneticVariation GWASCAT Genome-wide association study of schizophrenia in Ashkenazi Jews. 26198764

2015
dbSNP: rs8042374
rs8042374
CHRNA3
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		A 0.700 GeneticVariation GWASCAT Biological insights from 108 schizophrenia-associated genetic loci. 25056061

2014
dbSNP: rs8042374
rs8042374
CHRNA3
CUI: C1519383
Disease: Smoking Behaviors
Smoking Behaviors 		0.700 GeneticVariation GWASDB Genome-wide meta-analyses identify multiple loci associated with smoking behavior. 20418890

2010
dbSNP: rs8042374
rs8042374
CHRNA3
CUI: C1519383
Disease: Smoking Behaviors
Smoking Behaviors 		0.700 GeneticVariation GWASDB Meta-analysis and imputation refines the association of 15q25 with smoking quantity. 20418889

2010
dbSNP: rs8042374
rs8042374
CHRNA3
CUI: C2931822
Disease: Nasopharyngeal carcinoma
Nasopharyngeal carcinoma 		0.700 GeneticVariation GWASDB A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci. 20512145

2010
dbSNP: rs8042374
rs8042374
CHRNA3
CUI: C1519383
Disease: Smoking Behaviors
Smoking Behaviors 		0.700 GeneticVariation GWASDB Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 20418888

2010