|
rs1801394
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our overall analyses suggested that <i>MTRR</i> rs1801394, <i>MTRR</i> rs1532268, <i>MTHFR</i> rs1801131 and <i>MTHFR</i> rs1801133 polymorphisms were all significantly associated with the risk of CHD in certain genetic models.
|
30333252 |
2018 |
|
rs1801394
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Also, MTRR A66G and C524T polymorphisms were associated with a higher CHD risk in the homozygote comparison of wild and mutant genotypes and also in heterozygote and mutant comparison.
|
28778621 |
2017 |
|
rs1801394
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Evidence is mounting for the association between MTRR A66G (rs1801394)/MTR A2756G (rs1805087) and the CHD risk, but results are controversial.
|
24595101 |
2014 |
|
rs1801394
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The results showed that MTRR A66G polymorphism was associated with a higher CHD risk in the allele comparison (G vs A: OR 1.163; 95 % CI 1.016-1.330; P heterogeneity = 0.004), the homozygote comparison (GG vs AA: OR 1.332; 95 % CI 1.020-1.740; P heterogeneity = 0.035), and the dominant model (GG/AG vs AA: OR 1.218; 95 % CI 1.001-1.482; P heterogeneity = 0.001).
|
24913415 |
2014 |
|
rs1801394
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests that MTR A2756G polymorphism, but not MTRR A66G and MTHFR A1298C, is associated with risk of CHD for Europeans.
|
21780915 |
2012 |
|
rs1801394
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Folate gene polymorphisms MTR A2756G, MTRR A66G, and BHMT G742A and risk for coronary artery disease: a meta-analysis.
|
22339686 |
2012 |
|
rs1801394
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
In conclusion, MTRR A66G and C524T polymorphisms are associated with increased risk of CHDs.
|
22057956 |
2011 |
|
rs1801394
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
These data indicate that maternal MTRR 66A>G polymorphism is not a risk factor for CHD.
|
17087642 |
2006 |
|
rs1801394
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
We studied several single nucleotide polymorphisms (SNP) in Hcy-regulating genes [methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C; methionine synthase (MS) A2756G; methionine synthase reductase (MTRR) A66G] in relation to total plasma Hcy levels, transplant coronary artery disease and thromboembolic episodes in 84 heart transplant patients, and we compared the incidence of these polymorphisms with those in a healthy adult controls.
|
15612980 |
2005 |
|
rs1801394
|
|
Coronary heart disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Methylenetetrahydrofolate reductase (MTHFR) 677C>T and methionine synthase reductase (MTRR) 66A>G polymorphisms: association with serum homocysteine and angiographic coronary artery disease in the era of flour products fortified with folic acid.
|
12801615 |
2003 |