Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4986790
rs4986790
TLR4
CUI: C0025303
Disease: Meningococcal Infections
Meningococcal Infections 		0.030 GeneticVariation BEFREE We could not observe a significant influence of CD14 C-159T and TLR4 Asp299Gly polymorphisms on the risk of developing IMD in surviving meningococcal disease patients. 19809507

2009
dbSNP: rs4986790
rs4986790
TLR4
CUI: C0025303
Disease: Meningococcal Infections
Meningococcal Infections 		0.030 GeneticVariation BEFREE We investigated an association between 2 TLR4 mutations (Asp(299)Gly and Thr(399)Ile) and meningococcal disease in 197 patients and 214 healthy controls by allele-specific real time polymerase chain reaction and direct sequencing. 16395111

2006
dbSNP: rs4986790
rs4986790
TLR4
CUI: C0025303
Disease: Meningococcal Infections
Meningococcal Infections 		0.030 GeneticVariation BEFREE The allele frequency of the Asp299Gly polymorphism was 5.9% among 879 blood donors, 6.5% among 1047 patients with microbiologically proven meningococcal disease, and 4.1% among 86 patients who died of meningococcal disease. 11494169

2001