Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800562
rs1800562
HFE ; LOC108783645
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.030 GeneticVariation BEFREE No greater prevalence of C282Y homozygosity mutation or elevated serum ferritin or transferrin saturation levels was found in the study cohort with severe osteoarthritis of the hip than in controls from the general population. 30427934

2018
dbSNP: rs1800562
rs1800562
HFE ; LOC108783645
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.030 GeneticVariation BEFREE HFE C282Y homozygosity was associated with an increased risk of both single and bilateral total hip replacement for osteoarthritis. 22209421

2012
dbSNP: rs1800562
rs1800562
HFE ; LOC108783645
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.030 GeneticVariation BEFREE This is the first report to show an increased risk of OA among individuals who are heterozygous for the C282Y HFE mutation. 12508400

2003