Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799945
rs1799945
HFE ; LOC108783645
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.050 GeneticVariation BEFREE The meta-analysis indicated that C282Y and H63D polymorphisms in the HFE gene might not be associated with PD. 26340960

2016
dbSNP: rs1799945
rs1799945
HFE ; LOC108783645
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.050 GeneticVariation BEFREE The association between the C282Y and H63D polymorphisms of HFE gene and the risk of Parkinson's disease: A meta-analysis. 25863172

2015
dbSNP: rs1799945
rs1799945
HFE ; LOC108783645
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.050 GeneticVariation BEFREE We examined four known polymorphisms, C282Y and H63D in the HFE gene, G258S in the TF gene and S82G in the TFR gene, in 181 sporadic PD patients and 180 controls from Southern Italy to investigate their possible role in susceptibility to PD. 21384276

2011
dbSNP: rs1799945
rs1799945
HFE ; LOC108783645
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.050 GeneticVariation BEFREE We conclude that in the Italian population, the most common HFE mutations, H63D and C282Y are not associated with the individual risk to develop PD, nor have specific influence on the clinical features of the disease. 18325820

2008
dbSNP: rs1799945
rs1799945
HFE ; LOC108783645
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.050 GeneticVariation BEFREE Recent studies on the role of hemochromatosis gene (HFE) mutations in PD vary from a protective effect of C282Y heterozygosity, no effect of the C282Y or H63D mutation to an increased risk for PD in C282Y mutation carriers. 16935420

2006