Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800629
rs1800629
TNF
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.030 GeneticVariation BEFREE For rs1800629, the A allele was also linked to reduced risk of AS (p < 0.0001, OR = 0.54, 95% CI = 0.39-0.74). 29230494

2018
dbSNP: rs1800629
rs1800629
TNF
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.030 GeneticVariation BEFREE While <i>TNF</i>-308 (rs1800629) AA/GA, <i>IL17A</i> (rs2275913) AA/GA, and <i>IL17F</i> (rs763780) CC/TC genotype frequencies were associated, in the dominance inheritance model, with SpA and AS, regardless of gender, the presence of <i>HLA-B27</i>, <i>TNF</i>-238 (rs361525) GA/AA, <i>IL17A</i> (rs2275913) AA/GA, and <i>IL17F</i> (rs763780) genotypes was associated with PsA. 29849482

2018
dbSNP: rs1800629
rs1800629
TNF
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.030 GeneticVariation BEFREE We replicated associations between AS and the polymorphisms in TNF (rs1800629), TNFRSF1A (rs4149570), and IL23R (rs11209026). 30208882

2018
dbSNP: rs1799964
rs1799964
LTA ; TNF ; LOC100287329
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.010 GeneticVariation BEFREE For rs1799964, the C allele was linked to reduced risk of AS (p < 0.0001, OR = 0.60, 95% CI = 0.50-0.71). 29230494

2018
dbSNP: rs1800630
rs1800630
LTA ; TNF ; LOC100287329
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.010 GeneticVariation BEFREE For rs1800630, the A allele was also linked to reduced risk of AS (p < 0.0001, OR = 0.59, 95% CI = 0.48-0.72). 29230494

2018