Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4986790
rs4986790
TLR4
CUI: C0577631
Disease: Carotid Atherosclerosis
Carotid Atherosclerosis 		0.040 GeneticVariation BEFREE Recently, the common Asp299Gly polymorphism of the Toll-like receptor 4 (TLR-4) was found to be associated with a reduced incidence of acute myocardial infarction and carotid atherosclerosis. 17587646

2007
dbSNP: rs4986790
rs4986790
TLR4
CUI: C0577631
Disease: Carotid Atherosclerosis
Carotid Atherosclerosis 		0.040 GeneticVariation BEFREE The presence of the D299G and T399I polymorphisms of the TLR-4 gene does not play a major role on the progression of carotid atherosclerosis. 15953129

2005
dbSNP: rs4986790
rs4986790
TLR4
CUI: C0577631
Disease: Carotid Atherosclerosis
Carotid Atherosclerosis 		0.040 GeneticVariation BEFREE This implies that the Asp299Gly TLR4-allele might have a protective role in carotid atherosclerosis, but not in cerebral ischemia. 15258789

2004
dbSNP: rs4986790
rs4986790
TLR4
CUI: C0577631
Disease: Carotid Atherosclerosis
Carotid Atherosclerosis 		0.040 GeneticVariation BEFREE The Asp299Gly polymorphism in the toll-like receptor 4 (TLR4) gene reduces responsiveness to lipopolysaccharide and has been associated with reduced incidence and slower progression of carotid atherosclerosis. 12957699

2003