Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1229984
rs1229984
ADH1B
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.050 GeneticVariation BEFREE Moreover, under dominant and recessive models, ADH1B Arg4</span>7His variant genotypes were associated with greater susceptibility to CRC when compared with the wild-type sequence. 27706775

2016
dbSNP: rs1229984
rs1229984
ADH1B
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.050 GeneticVariation BEFREE The current meta-analysis has established that ADH1B (rs1229984) and PPARG (rs1801282) are two risk variants of CRC. 24552298

2014
dbSNP: rs1229984
rs1229984
ADH1B
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.050 GeneticVariation BEFREE Moreover, the SNPs rs1229984 in ADH1B gene was found to be associated with CRC risk: under the recessive model, the OR was 1.75 for A/A genotype (95%CI = 1.21-2.52; p-value = 0.0025). 24282520

2013
dbSNP: rs1229984
rs1229984
ADH1B
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.050 GeneticVariation BEFREE The rs1229984 (ADH1B), rs1573496 (ADH7) and rs441 (ALDH2) polymorphisms were not associated with CRC risk overall in Western-European populations. 23149980

2012
dbSNP: rs1229984
rs1229984
ADH1B
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.050 GeneticVariation BEFREE A gene-gene interaction between ALDH2 Glu487Lys and ADH2 His47Arg polymorphisms regarding the risk of colorectal cancer in Japan. 16332725

2006