Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800629
rs1800629
TNF
CUI: C1719672
Disease: Severe Sepsis
Severe Sepsis 		0.020 GeneticVariation BEFREE The genotype results demonstrated that carriers of the TNF-α rs1800629 A allele had a 4.28-fold higher risk for septic shock (adjusted odds ratio [OR], 4.28; 95% confidence interval [CI], 2.24-8.18; P < .01) compared with severe sepsis, and carriers of the IL-6 rs1800795 C allele had a 2.42-fold higher risk for septic shock (OR, 2.42; 95% CI, 1.08-5.45; P < .01) compared with severe sepsis. 26025100

2015
dbSNP: rs1800629
rs1800629
TNF
CUI: C1719672
Disease: Severe Sepsis
Severe Sepsis 		0.020 GeneticVariation BEFREE Our findings suggested that the functional TNF gene SNP rs1800629 was strongly associated with susceptibility to severe sepsis, but not with lethality in Chinese Han population. 23029405

2012