Source: CLINVAR

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		G 0.700 GeneticVariation CLINVAR Genetic mutation screen in early non--small-cell lung cancer (NSCLC) specimens. 24370118

2014
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		C 0.700 CausalMutation CLINVAR Characteristics of lung cancers harboring NRAS mutations. 23515407

2013
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		A 0.700 CausalMutation CLINVAR Characteristics of lung cancers harboring NRAS mutations. 23515407

2013
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		C 0.700 CausalMutation CLINVAR Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1. 22773810

2012
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		C 0.700 CausalMutation CLINVAR Cytostatic activity of adenosine triphosphate-competitive kinase inhibitors in BRAF mutant thyroid carcinoma cells. 19880792

2010
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		C 0.700 CausalMutation CLINVAR Somatic mutations affect key pathways in lung adenocarcinoma. 18948947

2008
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		A 0.700 CausalMutation CLINVAR Somatic mutations affect key pathways in lung adenocarcinoma. 18948947

2008
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		C 0.700 CausalMutation CLINVAR BRAF mutations in papillary carcinomas of the thyroid. 14508525

2003
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		A 0.700 CausalMutation CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918

2002
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		C 0.700 CausalMutation CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918

2002
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		C 0.700 CausalMutation CLINVAR ras gene mutations in non-small cell lung cancers are associated with shortened survival irrespective of treatment intent. 1654209

1991
dbSNP: rs11554290
rs11554290
NRAS
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		C 0.700 CausalMutation CLINVAR Mechanism of activation of an N-ras oncogene of SW-1271 human lung carcinoma cells. 6587382

1984