Source: CLINVAR

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs760146707
rs760146707
RAD50
CUI: C0027672
Disease: Neoplastic Syndromes, Hereditary
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer. 25452441

2015
dbSNP: rs760146707
rs760146707
RAD50
CUI: C0027672
Disease: Neoplastic Syndromes, Hereditary
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR Germline variants in MRE11/RAD50/NBN complex genes in childhood leukemia. 24093751

2013
dbSNP: rs760146707
rs760146707
RAD50
CUI: C0027672
Disease: Neoplastic Syndromes, Hereditary
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR RAD50 and NBS1 are not likely to be susceptibility genes in Chinese non-BRCA1/2 hereditary breast cancer. 21811815

2012
dbSNP: rs760146707
rs760146707
RAD50
CUI: C0027672
Disease: Neoplastic Syndromes, Hereditary
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR RAD50 gene mutations are not likely a risk factor for breast cancer in Poland. 20571869

2010
dbSNP: rs760146707
rs760146707
RAD50
CUI: C0027672
Disease: Neoplastic Syndromes, Hereditary
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR Some common mutations of RAD50 and NBS1 in western populations do not contribute significantly to Chinese non-BRCA1/2 hereditary breast cancer. 19904603

2010
dbSNP: rs760146707
rs760146707
RAD50
CUI: C0027672
Disease: Neoplastic Syndromes, Hereditary
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR Breast cancer susceptibility: current knowledge and implications for genetic counselling. 19092773

2009
dbSNP: rs760146707
rs760146707
RAD50
CUI: C0027672
Disease: Neoplastic Syndromes, Hereditary
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR Rad50 c.687delT does not contribute significantly to familial breast cancer in a French population. 19190165

2009
dbSNP: rs760146707
rs760146707
RAD50
CUI: C0027672
Disease: Neoplastic Syndromes, Hereditary
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability. 16474176

2006
dbSNP: rs760146707
rs760146707
RAD50
CUI: C0027672
Disease: Neoplastic Syndromes, Hereditary
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR Evaluation of RAD50 in familial breast cancer predisposition. 16385572

2006
dbSNP: rs760146707
rs760146707
RAD50
CUI: C0027672
Disease: Neoplastic Syndromes, Hereditary
Neoplastic Syndromes, Hereditary 		G 0.700 CausalMutation CLINVAR Mutation screening of Mre11 complex genes: indication of RAD50 involvement in breast and ovarian cancer susceptibility. 14684699

2003