Source: CLINVAR

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs587782111
rs587782111
MSH6 ; FBXO11
CUI: C1333990
Disease: Hereditary Nonpolyposis Colorectal Cancer
Hereditary Nonpolyposis Colorectal Cancer 		TA 0.700 CausalMutation CLINVAR Improving Mutation Screening in Patients with Colorectal Cancer Predisposition Using Next-Generation Sequencing. 28502729

2017
dbSNP: rs587782111
rs587782111
MSH6 ; FBXO11
CUI: C1333990
Disease: Hereditary Nonpolyposis Colorectal Cancer
Hereditary Nonpolyposis Colorectal Cancer 		TA 0.700 CausalMutation CLINVAR Rare disruptive mutations and their contribution to the heritable risk of colorectal cancer. 27329137

2016
dbSNP: rs587782111
rs587782111
MSH6 ; FBXO11
CUI: C1333990
Disease: Hereditary Nonpolyposis Colorectal Cancer
Hereditary Nonpolyposis Colorectal Cancer 		TA 0.700 CausalMutation CLINVAR Yield of routine molecular analyses in colorectal cancer patients ≤70 years to detect underlying Lynch syndrome. 22081473

2012
dbSNP: rs587782111
rs587782111
MSH6 ; FBXO11
CUI: C1333990
Disease: Hereditary Nonpolyposis Colorectal Cancer
Hereditary Nonpolyposis Colorectal Cancer 		TA 0.700 CausalMutation CLINVAR Comparison between universal molecular screening for Lynch syndrome and revised Bethesda guidelines in a large population-based cohort of patients with colorectal cancer. 21868491

2012
dbSNP: rs587782111
rs587782111
MSH6 ; FBXO11
CUI: C1333990
Disease: Hereditary Nonpolyposis Colorectal Cancer
Hereditary Nonpolyposis Colorectal Cancer 		TA 0.700 CausalMutation CLINVAR Cancer risks associated with germline mutations in MLH1, MSH2, and MSH6 genes in Lynch syndrome. 21642682

2011