Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 13 0.438 0.846 3.5E-21 0.700 None 0.899 9 4 2004 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 7 0.231 0.962 0.80 0.700 None 0.975 1 2 1989 2020
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 major histocompatibility complex, class II, DR beta 1 Immune response 18 0.333 0.923 1.1E-03 0.500 None 0.936 6 4 1989 2020
Entrez Id: 1235
Gene Symbol: CCR6
CCR6
P51684 C-C motif chemokine receptor 6 G-protein coupled receptor 4 0.485 0.808 5.8E-03 0.500 None 1.000 6 8 2001 2019
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
Q14765 signal transducer and activator of transcription 4 Nucleic acid binding 13 0.471 0.769 0.77 0.500 None 0.889 5 5 2000 2019
Entrez Id: 23569
Gene Symbol: PADI4
PADI4
Q9UM07 peptidyl arginine deiminase 4 1 0.494 0.808 4.6E-16 0.500 None 0.912 4 6 2003 2020
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
P01589 interleukin 2 receptor subunit alpha Receptor 14 0.389 0.885 5.5E-02 0.500 None 1.000 4 2 1992 2019
Entrez Id: 958
Gene Symbol: CD40
CD40
P25942 CD40 molecule 8 0.396 0.846 0.85 0.500 None 0.848 4 2 2002 2019
Entrez Id: 7185
Gene Symbol: TRAF1
TRAF1
Q13077 TNF receptor associated factor 1 Signaling 5 0.554 0.731 3.6E-03 0.500 None 0.850 4 2 2007 2019
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
P04440 major histocompatibility complex, class II, DP beta 1 Immune response 8 0.453 0.923 5.3E-10 0.500 None 0.938 3 62 1988 2020
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
Q13568 interferon regulatory factor 5 Transcription factor 4 0.489 0.731 9.0E-03 0.500 None 0.906 2 1 2006 2019
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
P21580 TNF alpha induced protein 3 Enzyme 5 0.481 0.808 1.00 0.500 None 1.000 2 2 2007 2018
Entrez Id: 3570
Gene Symbol: IL6R
IL6R
P08887 interleukin 6 receptor Signaling 11 0.471 0.846 3.2E-05 0.500 None 0.971 2 1 2001 2019
Entrez Id: 7189
Gene Symbol: TRAF6
TRAF6
Q9Y4K3 TNF receptor associated factor 6 Signaling 1 0.472 0.808 1.00 0.500 None 1.000 1 1 2008 2019
Entrez Id: 940
Gene Symbol: CD28
CD28
P10747 CD28 molecule 1 0.436 0.885 0.36 0.500 None 1.000 1 1 1996 2018
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
P29597 tyrosine kinase 2 Kinase 8 0.505 0.769 4.5E-08 0.490 None 1.000 2 1 2007 2019
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
Q01196 RUNX family transcription factor 1 Transcription factor 6 0.425 0.808 0.65 0.490 None 0.786 2 2 2003 2019
Entrez Id: 5771
Gene Symbol: PTPN2
PTPN2
P17706 protein tyrosine phosphatase non-receptor type 2 12 0.538 0.692 1.00 0.490 None 1.000 2 2 2012 2019
Entrez Id: 5788
Gene Symbol: PTPRC
PTPRC
P08575 protein tyrosine phosphatase receptor type C Enzyme 2 0.435 0.808 1.00 0.480 None 1.000 1 1 1991 2017
Entrez Id: 4795
Gene Symbol: NFKBIL1
NFKBIL1
Q9UBC1 NFKB inhibitor like 1 3 0.653 0.615 2.6E-02 0.470 None 1.000 3 4 2001 2011
Entrez Id: 3560
Gene Symbol: IL2RB
IL2RB
P14784 interleukin 2 receptor subunit beta Receptor 10 0.491 0.846 0.29 0.470 None 0.909 2 3 1992 2019
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor Receptor 6 0.420 0.885 6.4E-16 0.470 None 1.000 2 5 2002 2014
Entrez Id: 5966
Gene Symbol: REL
REL
Q04864 REL proto-oncogene, NF-kB subunit Transcription factor 3 0.579 0.692 1.00 0.460 None 0.909 4 2 2009 2019
Entrez Id: 3899
Gene Symbol: AFF3
AFF3
P51826 AF4/FMR2 family member 3 Transcription factor 4 0.623 0.692 1.00 0.460 None 1.000 3 3 2009 2016
Entrez Id: 79722
Gene Symbol: ANKRD55
ANKRD55
Q3KP44 ankyrin repeat domain 55 7 0.650 0.462 6.8E-08 0.440 None 1.000 4 3 2010 2019