Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 51752
Gene Symbol: ERAP1
ERAP1
Q9NZ08 endoplasmic reticulum aminopeptidase 1 Enzyme 156 0.556 0.692 2.1E-26 0.700 None 1.000 24 6 2013 2020
Entrez Id: 4210
Gene Symbol: MEFV
MEFV
O15553 MEFV innate immuity regulator, pyrin 410 0.440 0.885 1.0E-14 0.500 None 1.000 21 9 2000 2019
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 1519 0.288 0.962 0.47 0.100 None 1.000 15 0 2004 2019
Entrez Id: 3107
Gene Symbol: HLA-C
HLA-C
P10321 major histocompatibility complex, class I, C 435 0.415 0.846 1.6E-06 0.100 None 1.000 10 0 1996 2018
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 737 0.364 0.962 3.5E-02 0.380 None 1.000 10 2 1996 2016
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 950 0.336 0.885 0.48 0.090 None 1.000 9 0 2001 2017
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
P21580 TNF alpha induced protein 3 Enzyme 212 0.481 0.808 1.00 0.090 None 1.000 9 0 2013 2020
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.090 None 1.000 9 2 2000 2019
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 434 0.423 0.923 2.0E-30 0.180 None 1.000 8 6 2005 2019
Entrez Id: 51561
Gene Symbol: IL23A
IL23A
Q9NPF7 interleukin 23 subunit alpha Signaling 427 0.415 0.846 0.36 0.080 None 1.000 8 0 2008 2018
Entrez Id: 1234
Gene Symbol: CCR5
CCR5
P51681 C-C motif chemokine receptor 5 (gene/pseudogene) G-protein coupled receptor 508 0.398 0.885 4.3E-10 0.080 None 1.000 8 0 2004 2016
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
Q14765 signal transducer and activator of transcription 4 Nucleic acid binding 316 0.471 0.769 0.77 0.670 None 1.000 8 4 2010 2019
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1018 0.333 0.923 1.1E-03 0.070 None 1.000 7 0 1995 2020
Entrez Id: 3565
Gene Symbol: IL4
IL4
P05112 interleukin 4 996 0.332 0.962 4.7E-03 0.060 None 1.000 6 0 2003 2017
Entrez Id: 7421
Gene Symbol: VDR
VDR
P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.060 None 1.000 6 1 2012 2019
Entrez Id: 27178
Gene Symbol: IL37
IL37
Q9NZH6 interleukin 37 280 0.459 0.846 1.2E-04 0.060 None 1.000 6 1 2008 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.060 None 1.000 6 0 2004 2013
Entrez Id: 3593
Gene Symbol: IL12B
IL12B
P29460 interleukin 12B Signaling 249 0.480 0.885 1.1E-04 0.050 None 1.000 5 1 2006 2015
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.050 None 1.000 5 1 2007 2019
Entrez Id: 1230
Gene Symbol: CCR1
CCR1
P32246 C-C motif chemokine receptor 1 G-protein coupled receptor 192 0.531 0.769 0.39 0.540 None 1.000 5 0 2012 2019
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A
P19438 TNF receptor superfamily member 1A 487 0.409 0.923 0.99 0.150 None 1.000 5 2 2005 2019
Entrez Id: 3329
Gene Symbol: HSPD1
HSPD1
P10809 heat shock protein family D (Hsp60) member 1 398 0.432 0.808 0.99 0.050 None 1.000 5 0 2001 2017
Entrez Id: 90865
Gene Symbol: IL33
IL33
O95760 interleukin 33 487 0.409 0.885 8.3E-10 0.050 None 1.000 5 2 2013 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.050 None 1.000 5 2 2012 2017
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
P18510 interleukin 1 receptor antagonist 701 0.373 0.923 3.1E-02 0.050 None 1.000 5 0 2003 2017