Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
P51587 BRCA2 DNA repair associated Nucleic acid binding 8 0.379 0.846 2.4E-25 1.000 strong 0.951 24 69 1994 2020
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
P38398 BRCA1 DNA repair associated Enzyme 5 0.367 0.923 9.2E-29 1.000 strong 0.956 22 88 1992 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 10 0.292 0.923 1.00 1.000 None 0.985 1 6 2001 2020
Entrez Id: 580
Gene Symbol: BARD1
BARD1
Q99728 BRCA1 associated RING domain 1 3 0.597 0.538 1.4E-24 1.000 limited 0.896 0 1 1996 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 2 0.324 0.962 1.00 1.000 None 0.967 0 1 1983 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 6 0.236 0.962 0.53 1.000 None 0.973 0 0 1982 2020
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
Q86YC2 partner and localizer of BRCA2 1 0.485 0.769 3.0E-19 0.800 None 0.970 3 1 2006 2020
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
O96017 checkpoint kinase 2 Kinase 5 0.460 0.808 1.2E-24 0.800 None 0.963 3 1 2001 2019
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1
Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 3 0.507 0.731 6.2E-17 0.800 None 0.951 2 2 2001 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog Enzyme 10 0.305 0.923 0.26 0.800 strong 0.956 0 0 1997 2020
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 10 0.401 0.808 0.15 0.800 limited 1.000 0 2 1991 2019
Entrez Id: 857
Gene Symbol: CAV1
CAV1
Q03135 caveolin 1 Enzyme modulator 1 0.388 0.885 8.3E-03 0.800 None 0.977 0 1 1999 2019
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 3 0.311 0.962 0.98 0.700 limited 0.993 1 1 1999 2020
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
P21802 fibroblast growth factor receptor 2 Kinase 13 0.380 0.808 1.00 0.700 None 0.942 0 0 1991 2020
Entrez Id: 2033
Gene Symbol: EP300
EP300
Q09472 E1A binding protein p300 3 0.459 0.846 1.00 0.700 None 1.000 0 1 2004 2020
Entrez Id: 8438
Gene Symbol: RAD54L
RAD54L
Q92698 RAD54 like 3 0.633 0.423 2.4E-15 0.620 None 0.500 0 1 2017 2017
Entrez Id: 5888
Gene Symbol: RAD51
RAD51
Q06609 RAD51 recombinase 2 0.447 0.846 2.7E-02 0.600 None 0.957 2 1 1997 2019
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 2 0.465 0.808 1.00 0.600 None 1.000 0 1 2001 2019
Entrez Id: 2625
Gene Symbol: GATA3
GATA3
P23771 GATA binding protein 3 2 0.415 0.846 0.90 0.600 None 0.950 0 0 1999 2020
Entrez Id: 5245
Gene Symbol: PHB
PHB
P35232 prohibitin 1 0.511 0.846 0.76 0.600 None 0.944 0 2 1994 2018
Entrez Id: 4919
Gene Symbol: ROR1
ROR1
Q01973 receptor tyrosine kinase like orphan receptor 1 Kinase 6 0.552 0.731 1.00 0.600 None 1.000 0 1 2012 2020
Entrez Id: 2335
Gene Symbol: FN1
FN1
P02751 fibronectin 1 Signaling 4 0.365 0.962 1.4E-03 0.600 None 1.000 0 1 1997 2020
Entrez Id: 367
Gene Symbol: AR
AR
P10275 androgen receptor Nuclear receptor 4 0.351 0.846 0.99 0.600 None 0.947 0 2 1990 2020
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 1 0.364 0.923 4.0E-15 0.600 None 1.000 0 1 1998 2017
Entrez Id: 5744
Gene Symbol: PTHLH
PTHLH
P12272 parathyroid hormone like hormone 2 0.453 0.846 0.81 0.600 None 0.982 0 0 1992 2019