Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.200 None 0.950 20 34 1992 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.100 None 1.000 1 17 2016 2016
Entrez Id: 8405
Gene Symbol: SPOP
SPOP 		O43791 speckle type BTB/POZ protein 72 0.597 0.500 1.00 0.420 None 1.000 3 11 2014 2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1368 0.303 0.885 1.00 0.100 None 1.000 1 10 2016 2016
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.430 None 0.750 4 8 2006 2016
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.100 None 1.000 1 4 2016 2016
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 1349 0.305 0.923 0.26 0.480 None 1.000 9 2 2009 2019
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1 		Q02750 mitogen-activated protein kinase kinase 1 Kinase 389 0.439 0.846 0.90 0.300 None 1.000 2 2 2003 2016
Entrez Id: 1508
Gene Symbol: CTSB
CTSB 		P07858 cathepsin B Enzyme 304 0.457 0.846 5.9E-11 0.010 None 1.000 1 2 2010 2010
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.100 None 1.000 1 2 2016 2016
Entrez Id: 7514
Gene Symbol: XPO1
XPO1 		O14980 exportin 1 Receptor 178 0.504 0.692 1.00 0.100 None 1.000 1 2 2016 2016
Entrez Id: 9125
Gene Symbol: CNOT9
CNOT9 		Q92600 CCR4-NOT transcription complex subunit 9 12 0.769 0.192 0.99 0.100 None 1.000 1 2 2016 2016
Entrez Id: 5518
Gene Symbol: PPP2R1A
PPP2R1A 		P30153 protein phosphatase 2 scaffold subunit Aalpha Enzyme 104 0.588 0.577 0.98 0.100 None 1.000 1 2 2016 2016
Entrez Id: 3417
Gene Symbol: IDH1
IDH1 		O75874 isocitrate dehydrogenase (NADP(+)) 1 399 0.424 0.808 2.6E-12 0.100 None 1.000 1 2 2016 2016
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1 		P09211 glutathione S-transferase pi 1 610 0.383 0.923 1.4E-02 0.100 None 1.000 12 1 1998 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 995 0.328 0.923 6.0E-03 0.190 None 1.000 10 1 1993 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.110 None 1.000 2 1 2015 2016
Entrez Id: 9968
Gene Symbol: MED12
MED12 		Q93074 mediator complex subunit 12 Transcription factor 340 0.476 0.769 1.00 0.100 None 1.000 1 1 2016 2016
Entrez Id: 4193
Gene Symbol: MDM2
MDM2 		Q00987 MDM2 proto-oncogene Nucleic acid binding 702 0.362 0.846 1.00 0.010 None 1.000 1 1 2013 2013
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 747 0.367 0.923 9.2E-29 0.300 None 0 1
Entrez Id: 354
Gene Symbol: KLK3
KLK3 		P07288 kallikrein related peptidase 3 Enzyme 358 0.443 0.885 4.4E-06 0.100 None 0.900 30 0 1992 2020
Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1 		Q04609 folate hydrolase 1 Enzyme 311 0.453 0.885 6.2E-09 0.100 None 0.938 16 0 1997 2019
Entrez Id: 367
Gene Symbol: AR
AR 		P10275 androgen receptor Nuclear receptor 854 0.351 0.846 0.99 0.600 None 1.000 15 0 2002 2019
Entrez Id: 29968
Gene Symbol: PSAT1
PSAT1 		Q9Y617 phosphoserine aminotransferase 1 285 0.478 0.846 1.1E-08 0.100 None 1.000 11 0 1999 2019
Entrez Id: 5324
Gene Symbol: PLAG1
PLAG1 		Q6DJT9 PLAG1 zinc finger Transcription factor 219 0.493 0.808 1.00 0.100 None 1.000 11 0 1999 2019