Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3815
Gene Symbol: KIT
KIT
P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 715 0.366 0.808 0.98 0.300 None 0 0
Entrez Id: 5426
Gene Symbol: POLE
POLE
Q07864 DNA polymerase epsilon, catalytic subunit 151 0.526 0.731 8.0E-27 0.300 None 0 0
Entrez Id: 6615
Gene Symbol: SNAI1
SNAI1
O95863 snail family transcriptional repressor 1 243 0.474 0.808 0.22 0.200 None 0 0
Entrez Id: 354
Gene Symbol: KLK3
KLK3
P07288 kallikrein related peptidase 3 Enzyme 358 0.443 0.885 4.4E-06 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
P84022 SMAD family member 3 Transcription factor 470 0.415 0.923 0.80 0.010 None < 0.001 1 0 2008 2008
Entrez Id: 6524
Gene Symbol: SLC5A2
SLC5A2
P31639 solute carrier family 5 member 2 Transporter 214 0.499 0.769 4.9E-14 0.010 None < 0.001 1 0 2018 2018
Entrez Id: 407975
Gene Symbol: MIR17HG
MIR17HG
Q75NE6 miR-17-92a-1 cluster host gene 224 0.483 0.808 0.010 None < 0.001 1 0 2017 2017
Entrez Id: 673
Gene Symbol: BRAF
BRAF
P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1228 0.319 0.846 1.00 0.020 None 0.500 2 0 2015 2019
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
P09211 glutathione S-transferase pi 1 610 0.383 0.923 1.4E-02 0.020 None 0.500 2 1 2005 2015
Entrez Id: 55872
Gene Symbol: PBK
PBK
Q96KB5 PDZ binding kinase Kinase 121 0.541 0.769 1.2E-06 0.020 None 0.500 2 0 2017 2018
Entrez Id: 4087
Gene Symbol: SMAD2
SMAD2
Q15796 SMAD family member 2 Transcription factor 289 0.456 0.808 1.00 0.020 None 0.500 2 0 2008 2012
Entrez Id: 3586
Gene Symbol: IL10
IL10
P22301 interleukin 10 1679 0.281 0.923 5.9E-03 0.060 None 0.667 6 1 2003 2018
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.040 None 0.750 4 0 2008 2013
Entrez Id: 2952
Gene Symbol: GSTT1
GSTT1
P30711 glutathione S-transferase theta 1 541 0.393 0.923 1.5E-04 0.340 None 0.750 4 0 2011 2015
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
Q13635 patched 1 604 0.398 0.885 1.00 0.330 None 0.750 4 0 1998 2018
Entrez Id: 7517
Gene Symbol: XRCC3
XRCC3
O43542 X-ray repair cross complementing 3 184 0.505 0.769 1.9E-10 0.330 None 0.800 5 0 2000 2014
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 499 0.420 0.846 7.1E-20 0.400 None 0.923 13 3 1999 2017
Entrez Id: 7508
Gene Symbol: XPC
XPC
Q01831 XPC complex subunit, DNA damage recognition and repair factor Nucleic acid binding 211 0.504 0.808 3.7E-11 0.100 None 0.923 13 3 1996 2016
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.400 None 0.938 16 0 1998 2020
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.600 None 0.970 100 3 1991 2019
Entrez Id: 4157
Gene Symbol: MC1R
MC1R
Q01726 melanocortin 1 receptor G-protein coupled receptor 183 0.524 0.808 8.1E-11 0.100 None 1.000 53 3 1999 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
P01112 HRas proto-oncogene, GTPase Enzyme modulator 698 0.378 0.885 8.0E-02 0.350 None 1.000 12 0 1988 2015
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.100 None 1.000 11 1 1997 2017
Entrez Id: 7421
Gene Symbol: VDR
VDR
P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.100 None 1.000 11 1 2007 2017
Entrez Id: 5429
Gene Symbol: POLH
POLH
Q9Y253 DNA polymerase eta 44 0.663 0.462 3.5E-09 0.100 None 1.000 10 0 2003 2019