Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3643
Gene Symbol: INSR
INSR
P06213 insulin receptor Kinase 452 0.432 0.846 3.6E-05 0.520 None 1.000 3 0 2008 2020
Entrez Id: 836
Gene Symbol: CASP3
CASP3
P42574 caspase 3 Enzyme 819 0.351 0.923 0.10 0.510 None 1.000 3 0 2003 2017
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.510 None 1.000 2 2 2004 2012
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.500 None 1.000 2 0 2005 2008
Entrez Id: 847
Gene Symbol: CAT
CAT
P04040 catalase Enzyme 794 0.359 0.962 1.6E-10 0.330 None 1.000 4 1 2000 2019
Entrez Id: 4908
Gene Symbol: NTF3
NTF3
P20783 neurotrophin 3 Signaling 170 0.519 0.808 0.93 0.310 None 1.000 2 0 2001 2009
Entrez Id: 3082
Gene Symbol: HGF
HGF
P14210 hepatocyte growth factor Enzyme 671 0.374 0.885 1.00 0.310 None 1.000 2 0 2005 2015
Entrez Id: 231
Gene Symbol: AKR1B1
AKR1B1
P15121 aldo-keto reductase family 1 member B Enzyme 220 0.491 0.885 2.0E-05 0.300 None 1.000 11 0 1998 2019
Entrez Id: 6446
Gene Symbol: SGK1
SGK1
O00141 serum/glucocorticoid regulated kinase 1 Kinase 188 0.506 0.769 2.3E-03 0.300 None 1.000 1 0 2005 2005
Entrez Id: 2915
Gene Symbol: GRM5
GRM5
P41594 glutamate metabotropic receptor 5 G-protein coupled receptor 189 0.525 0.846 1.00 0.300 None 1.000 1 0 2010 2010
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.300 None 1.000 1 0 2010 2010
Entrez Id: 1129
Gene Symbol: CHRM2
CHRM2
P08172 cholinergic receptor muscarinic 2 G-protein coupled receptor 91 0.585 0.615 0.18 0.300 None 1.000 1 0 2010 2010
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
P48357 leptin receptor Signaling 416 0.433 0.808 0.99 0.300 None 1.000 1 0 2014 2014
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 1021 0.333 0.923 0.84 0.300 None 1.000 1 0 2010 2010
Entrez Id: 4311
Gene Symbol: MME
MME
P08473 membrane metalloendopeptidase Enzyme 470 0.407 0.808 1.5E-18 0.300 None 1.000 1 0 2009 2009
Entrez Id: 4803
Gene Symbol: NGF
NGF
P01138 nerve growth factor Signaling 616 0.391 0.885 0.82 0.250 None 1.000 6 0 1996 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF
P23560 brain derived neurotrophic factor Signaling 992 0.345 0.923 0.66 0.220 None 1.000 3 0 2002 2017
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 1801 0.276 0.962 0.13 0.220 None 1.000 3 0 2013 2019
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
P05019 insulin like growth factor 1 1206 0.318 0.885 0.27 0.210 None 1.000 2 0 2009 2017
Entrez Id: 4359
Gene Symbol: MPZ
MPZ
P25189 myelin protein zero 249 0.503 0.846 0.27 0.210 None 1.000 2 0 2010 2012
Entrez Id: 4804
Gene Symbol: NGFR
NGFR
P08138 nerve growth factor receptor Receptor 256 0.477 0.846 9.8E-02 0.210 None 1.000 2 0 1996 2003
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.210 None 1.000 2 0 2013 2019
Entrez Id: 8989
Gene Symbol: TRPA1
TRPA1
O75762 transient receptor potential cation channel subfamily A member 1 Ion channel 160 0.546 0.846 7.2E-35 0.210 None 1.000 2 0 2012 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.200 None 1.000 2 0 2007 2012
Entrez Id: 6720
Gene Symbol: SREBF1
SREBF1
P36956 sterol regulatory element binding transcription factor 1 159 0.518 0.808 1.5E-02 0.200 None 1.000 1 0 2009 2009