Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1719
Gene Symbol: DHFR
DHFR
P00374 dihydrofolate reductase Enzyme 191 0.513 0.808 3.4E-02 0.310 None 1.000 2 0 2011 2018
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 985 0.337 0.885 3.2E-10 0.100 None 0.946 37 2 1999 2019
Entrez Id: 875
Gene Symbol: CBS
CBS
P0DN79 P35520 cystathionine beta-synthase Enzyme 295 0.465 0.885 3.1E-05 0.040 None 1.000 4 0 2001 2017
Entrez Id: 4548
Gene Symbol: MTR
MTR
Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 245 0.482 0.808 2.4E-12 0.030 None 0.667 3 1 2009 2015
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.030 None 1.000 3 0 2006 2019
Entrez Id: 113235
Gene Symbol: SLC46A1
SLC46A1
Q96NT5 solute carrier family 46 member 1 Transporter 97 0.606 0.731 2.2E-02 0.030 None 1.000 3 0 2011 2015
Entrez Id: 5093
Gene Symbol: PCBP1
PCBP1
Q15365 poly(rC) binding protein 1 Enzyme 49 0.650 0.538 0.91 0.030 None 1.000 3 0 2011 2017
Entrez Id: 3558
Gene Symbol: IL2
IL2
P60568 interleukin 2 950 0.336 0.885 0.48 0.020 None 1.000 2 0 2006 2017
Entrez Id: 4552
Gene Symbol: MTRR
MTRR
Q9UBK8 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 207 0.502 0.808 2.2E-14 0.020 None 0.500 2 1 2015 2015
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1
P49768 presenilin 1 Enzyme 369 0.469 0.846 0.97 0.010 None 1.000 1 0 2006 2006
Entrez Id: 5860
Gene Symbol: QDPR
QDPR
P09417 quinoid dihydropteridine reductase Enzyme 45 0.691 0.500 1.5E-04 0.010 None 1.000 1 0 2018 2018
Entrez Id: 51164
Gene Symbol: DCTN4
DCTN4
Q9UJW0 dynactin subunit 4 253 0.472 0.846 0.73 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5111
Gene Symbol: PCNA
PCNA
P12004 proliferating cell nuclear antigen Nucleic acid binding 581 0.382 0.846 0.98 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5077
Gene Symbol: PAX3
PAX3
P23760 paired box 3 257 0.481 0.769 0.24 0.010 None 1.000 1 0 2008 2008
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
P46531 notch receptor 1 693 0.369 0.885 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 4656
Gene Symbol: MYOG
MYOG
P15173 myogenin Transcription factor 56 0.623 0.615 0.90 0.010 None 1.000 1 0 2018 2018
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.010 None 1.000 1 0 2018 2018
Entrez Id: 4522
Gene Symbol: MTHFD1
MTHFD1
P11586 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Enzyme 121 0.554 0.769 4.5E-03 0.010 None 1.000 1 0 2015 2015
Entrez Id: 407040
Gene Symbol: MIR34A
MIR34A
microRNA 34a 428 0.421 0.846 0.010 None 1.000 1 0 2019 2019
Entrez Id: 8878
Gene Symbol: SQSTM1
SQSTM1
Q13501 sequestosome 1 470 0.428 0.885 8.6E-04 0.010 None 1.000 1 0 2018 2018
Entrez Id: 5981
Gene Symbol: RFC1
RFC1
P35251 replication factor C subunit 1 144 0.541 0.808 0.97 0.010 None 1.000 1 0 2008 2008
Entrez Id: 8290
Gene Symbol: H3-4
H3-4
Q16695 H3.4 histone 26 0.711 0.538 1.7E-05 0.010 None 1.000 1 0 2017 2017
Entrez Id: 79971
Gene Symbol: WLS
WLS
Q5T9L3 Wnt ligand secretion mediator 166 0.513 0.731 2.0E-02 0.010 None 1.000 1 0 2020 2020
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.010 None 1.000 1 0 2005 2005
Entrez Id: 728
Gene Symbol: C5AR1
C5AR1
P21730 complement C5a receptor 1 G-protein coupled receptor 179 0.513 0.808 0.40 0.010 None 1.000 1 0 2013 2013