Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3949
Gene Symbol: LDLR
LDLR 		P01130 low density lipoprotein receptor 282 0.449 0.885 9.8E-24 0.900 strong 0.982 688 87 1964 2020
Entrez Id: 338
Gene Symbol: APOB
APOB 		P04114 apolipoprotein B 275 0.453 0.808 1.9E-16 0.700 strong 0.986 126 8 1979 2019
Entrez Id: 255738
Gene Symbol: PCSK9
PCSK9 		Q8NBP7 proprotein convertase subtilisin/kexin type 9 Enzyme 226 0.482 0.808 2.7E-17 0.500 strong 0.977 163 10 2003 2020
Entrez Id: 348
Gene Symbol: APOE
APOE 		P02649 apolipoprotein E 886 0.338 0.962 1.9E-03 0.400 None 0.875 15 1 1991 2020
Entrez Id: 26119
Gene Symbol: LDLRAP1
LDLRAP1 		Q5SW96 low density lipoprotein receptor adaptor protein 1 Signaling 32 0.641 0.538 6.5E-06 0.400 strong 1.000 12 1 2002 2019
Entrez Id: 1071
Gene Symbol: CETP
CETP 		P11597 cholesteryl ester transfer protein 157 0.512 0.731 1.2E-23 0.390 None 1.000 8 2 1997 2011
Entrez Id: 4023
Gene Symbol: LPL
LPL 		P06858 lipoprotein lipase Enzyme 232 0.474 0.808 1.3E-09 0.380 None 1.000 8 3 1993 2016
Entrez Id: 5444
Gene Symbol: PON1
PON1 		P27169 paraoxonase 1 387 0.409 0.885 9.8E-11 0.370 None 1.000 7 0 2000 2019
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR 		P04035 3-hydroxy-3-methylglutaryl-CoA reductase 120 0.529 0.692 1.00 0.360 None 1.000 6 1 1975 2016
Entrez Id: 64240
Gene Symbol: ABCG5
ABCG5 		Q9H222 ATP binding cassette subfamily G member 5 Transporter 42 0.592 0.577 3.1E-21 0.330 strong 1.000 3 0 2010 2018
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1 		O95477 ATP binding cassette subfamily A member 1 Transporter 219 0.467 0.846 1.5E-13 0.330 None 1.000 3 1 2003 2019
Entrez Id: 64241
Gene Symbol: ABCG8
ABCG8 		Q9H221 ATP binding cassette subfamily G member 8 Transporter 52 0.573 0.538 2.4E-20 0.320 strong 1.000 2 0 2009 2019
Entrez Id: 337
Gene Symbol: APOA4
APOA4 		P06727 apolipoprotein A4 74 0.582 0.577 5.5E-06 0.320 None 1.000 2 0 1998 2005
Entrez Id: 3990
Gene Symbol: LIPC
LIPC 		P11150 lipase C, hepatic type Enzyme 57 0.585 0.654 3.3E-07 0.320 None 1.000 2 0 2005 2014
Entrez Id: 5445
Gene Symbol: PON2
PON2 		Q15165 paraoxonase 2 85 0.566 0.808 5.4E-05 0.320 None 1.000 2 1 2001 2006
Entrez Id: 6721
Gene Symbol: SREBF2
SREBF2 		Q12772 sterol regulatory element binding transcription factor 2 87 0.566 0.577 0.21 0.310 None 1.000 1 0 2002 2018
Entrez Id: 26228
Gene Symbol: STAP1
STAP1 		Q9ULZ2 signal transducing adaptor family member 1 Receptor 7 0.792 0.231 1.7E-05 0.140 None 1.000 4 0 2016 2020
Entrez Id: 4018
Gene Symbol: LPA
LPA 		P08519 lipoprotein(a) Enzyme 318 0.444 0.769 6.6E-89 0.100 None 0.953 43 1 1991 2019
Entrez Id: 1950
Gene Symbol: EGF
EGF 		P01133 epidermal growth factor 717 0.357 0.923 8.5E-17 0.060 None 1.000 6 0 1994 2015
Entrez Id: 335
Gene Symbol: APOA1
APOA1 		P02647 apolipoprotein A1 322 0.429 0.885 5.5E-04 0.060 None 1.000 6 0 1998 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP 		P02741 C-reactive protein 1410 0.299 0.962 3.7E-03 0.040 None 0.750 4 0 2007 2015
Entrez Id: 10599
Gene Symbol: SLCO1B1
SLCO1B1 		Q9Y6L6 solute carrier organic anion transporter family member 1B1 Transporter 124 0.538 0.731 1.1E-21 0.040 None 0.750 4 1 2006 2016
Entrez Id: 3988
Gene Symbol: LIPA
LIPA 		P38571 lipase A, lysosomal acid type Enzyme 85 0.564 0.654 5.5E-07 0.030 None 1.000 3 0 2016 2020
Entrez Id: 27329
Gene Symbol: ANGPTL3
ANGPTL3 		Q9Y5C1 angiopoietin like 3 Signaling 75 0.584 0.577 1.6E-13 0.030 None 1.000 3 0 2017 2019
Entrez Id: 6401
Gene Symbol: SELE
SELE 		P16581 selectin E 291 0.447 0.808 7.9E-10 0.030 None 1.000 3 0 2000 2017