Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.400 None 0.913 23 0 1994 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.400 None 1.000 11 0 1999 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.050 None 1.000 5 0 1995 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.050 None 1.000 5 0 1997 2014
Entrez Id: 2984
Gene Symbol: GUCY2C
GUCY2C
P25092 guanylate cyclase 2C Kinase 88 0.599 0.577 1.4E-30 0.040 None 1.000 4 0 2010 2018
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.030 None 1.000 3 0 1997 2014
Entrez Id: 9201
Gene Symbol: DCLK1
DCLK1
O15075 doublecortin like kinase 1 Kinase 123 0.545 0.615 1.00 0.030 None 1.000 3 0 2015 2018
Entrez Id: 3280
Gene Symbol: HES1
HES1
Q14469 hes family bHLH transcription factor 1 Transcription factor 243 0.468 0.885 0.71 0.030 None 1.000 3 0 2011 2017
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
MT-CO2 pseudogene 12 703 0.368 0.962 0.030 None 1.000 3 0 1997 2014
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.020 None 1.000 2 0 2002 2017
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.020 None 1.000 2 0 2012 2013
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.020 None 1.000 2 0 1993 2000
Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
Q9Y2T1 axin 2 169 0.507 0.692 0.57 0.020 None 1.000 2 0 2002 2013
Entrez Id: 4163
Gene Symbol: MCC
MCC
P23508 MCC regulator of WNT signaling pathway 110 0.568 0.731 4.7E-16 0.020 None 1.000 2 0 2008 2010
Entrez Id: 5629
Gene Symbol: PROX1
PROX1
Q92786 prospero homeobox 1 Transcription factor 114 0.565 0.538 1.00 0.020 None 1.000 2 0 2008 2014
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.020 None 1.000 2 0 2006 2013
Entrez Id: 6925
Gene Symbol: TCF4
TCF4
P15884 transcription factor 4 Transcription factor 378 0.464 0.846 1.00 0.020 None 1.000 2 0 2007 2011
Entrez Id: 4640
Gene Symbol: MYO1A
MYO1A
Q9UBC5 myosin IA Cellular structure 16 0.769 0.269 8.9E-46 0.020 None 1.000 2 0 2012 2013
Entrez Id: 595
Gene Symbol: CCND1
CCND1
P24385 cyclin D1 Enzyme modulator 859 0.344 0.923 0.89 0.020 None 1.000 2 0 2004 2004
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.020 None 0.500 2 0 2016 2018
Entrez Id: 6662
Gene Symbol: SOX9
SOX9
P48436 SRY-box transcription factor 9 466 0.419 0.846 1.00 0.020 None 1.000 2 0 2015 2016
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 1519 0.288 0.962 0.47 0.020 None 1.000 2 0 2015 2015
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
P43246 mutS homolog 2 Nucleic acid binding 490 0.406 0.808 0.90 0.020 None 1.000 2 0 1993 2013
Entrez Id: 8549
Gene Symbol: LGR5
LGR5
O75473 leucine rich repeat containing G protein-coupled receptor 5 G-protein coupled receptor 131 0.542 0.654 2.5E-08 0.020 None 1.000 2 0 2017 2018
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 257 0.465 0.808 1.00 0.020 None 1.000 2 0 2010 2011