Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
P43246 mutS homolog 2 Nucleic acid binding 490 0.406 0.808 0.90 0.020 None 1.000 2 0 1993 2013
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
P40692 mutL homolog 1 Nucleic acid binding 526 0.399 0.808 3.4E-05 0.020 None 1.000 2 0 1993 2000
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.400 None 0.913 23 0 1994 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.050 None 1.000 5 0 1995 2019
Entrez Id: 7432
Gene Symbol: VIP
VIP
P01282 vasoactive intestinal peptide Signaling 376 0.437 0.846 4.2E-04 0.010 None 1.000 1 0 1995 1995
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.050 None 1.000 5 0 1997 2014
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.030 None 1.000 3 0 1997 2014
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
MT-CO2 pseudogene 12 703 0.368 0.962 0.030 None 1.000 3 0 1997 2014
Entrez Id: 5320
Gene Symbol: PLA2G2A
PLA2G2A
P14555 phospholipase A2 group IIA Enzyme 215 0.488 0.808 9.7E-02 0.020 None 1.000 2 0 1998 2000
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.400 None 1.000 11 0 1999 2016
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.300 None 1.000 1 0 1999 1999
Entrez Id: 9126
Gene Symbol: SMC3
SMC3
Q9UQE7 structural maintenance of chromosomes 3 193 0.535 0.846 1.00 0.010 None 1.000 1 0 2000 2000
Entrez Id: 2980
Gene Symbol: GUCA2A
GUCA2A
Q02747 guanylate cyclase activator 2A 45 0.663 0.462 0.29 0.010 None 1.000 1 0 2000 2000
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
P38936 cyclin dependent kinase inhibitor 1A 490 0.403 0.769 1.9E-03 0.300 None 1.000 2 0 2001 2002
Entrez Id: 2118
Gene Symbol: ETV4
ETV4
P43268 ETS variant transcription factor 4 Transcription factor 120 0.545 0.500 2.9E-08 0.010 None 1.000 1 0 2001 2001
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
P09237 matrix metallopeptidase 7 Enzyme 320 0.446 0.885 1.0E-09 0.010 None 1.000 1 0 2001 2001
Entrez Id: 51176
Gene Symbol: LEF1
LEF1
Q9UJU2 lymphoid enhancer binding factor 1 211 0.486 0.769 1.00 0.010 None 1.000 1 0 2001 2001
Entrez Id: 5578
Gene Symbol: PRKCA
PRKCA
P17252 protein kinase C alpha Kinase 368 0.440 0.846 0.37 0.310 None 1.000 2 0 2002 2009
Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
Q9Y2T1 axin 2 169 0.507 0.692 0.57 0.020 None 1.000 2 0 2002 2013
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor Kinase 1394 0.295 0.885 0.37 0.020 None 1.000 2 0 2002 2017
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
P06731 CEA cell adhesion molecule 5 428 0.420 0.846 4.2E-10 0.020 None 1.000 2 0 2002 2004
Entrez Id: 4583
Gene Symbol: MUC2
MUC2
Q02817 mucin 2, oligomeric mucus/gel-forming Enzyme modulator 225 0.486 0.808 9.4E-10 0.310 None 1.000 2 0 2002 2008
Entrez Id: 641
Gene Symbol: BLM
BLM
P54132 BLM RecQ like helicase 158 0.535 0.808 1.5E-15 0.010 None 1.000 1 0 2002 2002
Entrez Id: 10
Gene Symbol: NAT2
NAT2
P11245 N-acetyltransferase 2 Enzyme 311 0.451 0.885 3.3E-06 0.010 None 1.000 1 0 2002 2002
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
Q05655 protein kinase C delta Kinase 287 0.480 0.846 1.00 0.300 None 1.000 1 0 2002 2002