Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 transcription factor 1773 0.251 0.897 0.17 0.600 0.898 452 8 1991 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
P04626 erb-b2 receptor tyrosine kinase 2 650 0.352 0.862 1.8E-03 0.400 0.932 382 2 1989 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
P15692 vascular endothelial growth factor A signaling molecule 1174 0.298 0.897 2.7E-05 0.400 0.951 366 3 1994 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
P00533 epidermal growth factor receptor 892 0.325 0.862 0.50 0.400 0.944 295 3 1989 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 hydrolase; protease 790 0.339 0.862 7.0E-18 0.400 0.974 289 3 1996 2018
Entrez Id: 960
Gene Symbol: CD44
CD44
P16070 CD44 molecule (Indian blood group) 467 0.389 0.862 2.1E-07 0.400 0.948 257 0 1990 2018
Entrez Id: 4830
Gene Symbol: NME1
NME1
P15531 NME/NM23 nucleoside diphosphate kinase 1 242 0.470 0.759 3.1E-03 0.400 0.915 253 1 1989 2017
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
P61073 C-X-C motif chemokine receptor 4 474 0.391 0.897 1.4E-02 0.400 0.987 245 1 2001 2018
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 hydrolase; protease 628 0.373 0.862 0.84 0.400 0.979 207 0 1993 2018
Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
P48061 C-X-C motif chemokine ligand 12 350 0.421 0.724 0.13 0.400 0.978 143 1 2001 2018
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
P10451 secreted phosphoprotein 1 481 0.391 0.862 1.0E-06 0.400 0.993 141 1 1996 2018
Entrez Id: 6275
Gene Symbol: S100A4
S100A4
P26447 S100 calcium binding protein A4 calcium-binding protein; signaling molecule 194 0.483 0.621 6.7E-03 0.400 0.947 134 0 1992 2017
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 nucleic acid binding; receptor; transcription factor 686 0.355 0.897 1.00 0.400 0.953 133 1 1992 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase enzyme modulator 886 0.350 0.724 9.0E-04 0.400 0.902 124 4 1991 2018
Entrez Id: 3732
Gene Symbol: CD82
CD82
P27701 CD82 molecule 118 0.533 0.586 9.9E-09 0.400 0.957 121 0 1995 2017
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
P60484 phosphatase and tensin homolog hydrolase; phosphatase 915 0.334 0.828 0.82 0.400 0.975 120 0 1997 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 oxidoreductase 832 0.338 0.897 1.00 0.400 0.931 116 0 1998 2018
Entrez Id: 3082
Gene Symbol: HGF
HGF
P14210 hepatocyte growth factor hydrolase; protease 478 0.394 0.793 1.00 0.400 0.981 113 0 1994 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha kinase; transferase 835 0.341 0.897 1.00 0.400 0.954 111 2 2004 2018
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 nucleic acid binding; transcription factor 706 0.358 0.862 1.00 0.400 0.991 110 0 2001 2018
Entrez Id: 10855
Gene Symbol: HPSE
HPSE
Q9Y251 heparanase hydrolase 230 0.464 0.759 2.2E-14 0.400 0.959 106 0 1999 2017
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
P00749 plasminogen activator, urokinase hydrolase; protease 325 0.434 0.690 2.1E-06 0.400 0.958 99 0 1993 2017
Entrez Id: 4233
Gene Symbol: MET
MET
P08581 MET proto-oncogene, receptor tyrosine kinase 407 0.405 0.793 0.99 0.400 0.898 91 2 1995 2017
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 129 0.519 0.724 0.400 0.976 83 0 2003 2018
Entrez Id: 1950
Gene Symbol: EGF
EGF
P01133 epidermal growth factor 494 0.386 0.897 1.0E-16 0.400 0.963 81 0 1989 2018