Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 703 0.373 0.962 1.00 0.110 None 1.000 160 257 1991 2017
Entrez Id: 160140
Gene Symbol: C11orf65
C11orf65 		Q8NCR3 chromosome 11 open reading frame 65 45 0.670 0.462 2.0E-14 0.100 None 1.000 159 220 1996 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.110 None 1.000 135 49 1994 2017
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		Q86YC2 partner and localizer of BRCA2 260 0.485 0.769 3.0E-19 0.100 None 1.000 110 293 2007 2017
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		P12830 cadherin 1 508 0.401 0.808 0.15 0.130 None 1.000 68 87 1994 2019
Entrez Id: 201163
Gene Symbol: FLCN
FLCN 		Q8NFG4 folliculin 160 0.537 0.885 0.79 0.100 None 1.000 59 58 2000 2019
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		O43502 RAD51 paralog C 162 0.533 0.692 6.2E-14 0.100 None 1.000 50 65 2002 2017
Entrez Id: 6391
Gene Symbol: SDHC
SDHC 		Q99643 succinate dehydrogenase complex subunit C 202 0.517 0.846 2.0E-04 0.100 None 1.000 35 16 2003 2018
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		Q92878 RAD50 double strand break repair protein 110 0.556 0.808 3.4E-27 0.100 None 1.000 31 164 1999 2017
Entrez Id: 5892
Gene Symbol: RAD51D
RAD51D 		O75771 RAD51 paralog D 36 0.674 0.385 1.1E-09 0.100 None 1.000 31 51 1982 2018
Entrez Id: 580
Gene Symbol: BARD1
BARD1 		Q99728 BRCA1 associated RING domain 1 75 0.597 0.538 1.4E-24 0.100 None 1.000 28 105 2003 2017
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13 		Q92826 homeobox B13 90 0.573 0.462 3.7E-08 0.100 None 1.000 26 1 1996 2017
Entrez Id: 641
Gene Symbol: BLM
BLM 		P54132 BLM RecQ like helicase 158 0.535 0.808 1.5E-15 0.100 None 1.000 26 10 1995 2016
Entrez Id: 2176
Gene Symbol: FANCC
FANCC 		Q00597 FA complementation group C 218 0.507 0.808 2.8E-13 0.100 None 1.000 23 6 1993 2017
Entrez Id: 4286
Gene Symbol: MITF
MITF 		O75030 melanocyte inducing transcription factor 244 0.499 0.808 0.98 0.100 None 1.000 22 1 1987 2016
Entrez Id: 4361
Gene Symbol: MRE11
MRE11 		P49959 MRE11 homolog, double strand break repair nuclease 171 0.527 0.808 1.3E-12 0.100 None 1.000 21 55 1999 2017
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		Q13635 patched 1 604 0.398 0.885 1.00 0.100 None 1.000 11 44 1997 2014
Entrez Id: 101927761
Gene Symbol: TH2LCRR
TH2LCRR 		T helper type 2 locus control region associated RNA 19 0.751 0.385 0.100 None 1.000 10 22 2000 2017
Entrez Id: 4360
Gene Symbol: MRC1
MRC1 		P22897 mannose receptor C-type 1 431 0.413 0.846 0.94 0.080 None 1.000 8 0 1999 2016
Entrez Id: 5424
Gene Symbol: POLD1
POLD1 		P28340 DNA polymerase delta 1, catalytic subunit 189 0.507 0.769 2.4E-06 0.100 None 1.000 7 2 2006 2017
Entrez Id: 54949
Gene Symbol: SDHAF2
SDHAF2 		Q9NX18 succinate dehydrogenase complex assembly factor 2 85 0.604 0.692 2.8E-06 0.110 None 1.000 7 3 2009 2017
Entrez Id: 5426
Gene Symbol: POLE
POLE 		Q07864 DNA polymerase epsilon, catalytic subunit 151 0.526 0.731 8.0E-27 0.100 None 1.000 6 2 1996 2015
Entrez Id: 4221
Gene Symbol: MEN1
MEN1 		O00255 menin 1 364 0.444 0.808 1.00 0.050 None 1.000 5 106 1999 2010
Entrez Id: 55654
Gene Symbol: TMEM127
TMEM127 		O75204 transmembrane protein 127 72 0.638 0.615 1.3E-02 0.100 None 1.000 4 6 2010 2016
Entrez Id: 7516
Gene Symbol: XRCC2
XRCC2 		O43543 X-ray repair cross complementing 2 187 0.512 0.731 4.0E-07 0.100 None 1.000 3 2 2012 2017