Source: ALL
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		Q9UIF7 mutY DNA glycosylase Enzyme 156 0.521 0.769 1.3E-18 0.100 None 1.000 123 83 2001 2017
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		Q86YC2 partner and localizer of BRCA2 260 0.485 0.769 3.0E-19 0.100 None 1.000 110 293 2007 2017
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		O96017 checkpoint kinase 2 Kinase 297 0.460 0.808 1.2E-24 0.100 None 1.000 106 133 1999 2019
Entrez Id: 6392
Gene Symbol: SDHD
SDHD 		O14521 succinate dehydrogenase complex subunit D Transporter 348 0.472 0.885 0.34 0.100 None 1.000 72 31 1998 2016
Entrez Id: 5925
Gene Symbol: RB1
RB1 		P06400 RB transcriptional corepressor 1 Nucleic acid binding 339 0.444 0.885 1.00 0.100 None 1.000 71 103 1989 2018
Entrez Id: 201163
Gene Symbol: FLCN
FLCN 		Q8NFG4 folliculin 160 0.537 0.885 0.79 0.100 None 1.000 59 58 2000 2019
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1 		Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 194 0.507 0.731 6.2E-17 0.100 None 1.000 56 145 2004 2017
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C 		O43502 RAD51 paralog C 162 0.533 0.692 6.2E-14 0.100 None 1.000 50 65 2002 2017
Entrez Id: 6389
Gene Symbol: SDHA
SDHA 		P31040 succinate dehydrogenase complex flavoprotein subunit A Enzyme 246 0.517 0.731 2.6E-10 0.100 None 1.000 42 28 1995 2018
Entrez Id: 23164
Gene Symbol: MPRIP
MPRIP 		Q6WCQ1 myosin phosphatase Rho interacting protein Enzyme modulator 113 0.556 0.885 0.98 0.100 None 1.000 37 25 2000 2019
Entrez Id: 4683
Gene Symbol: NBN
NBN 		O60934 nibrin Nucleic acid binding 291 0.467 0.808 2.2E-16 0.100 None 1.000 36 92 1998 2017
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		Q13485 SMAD family member 4 Transcription factor 575 0.401 0.808 1.00 0.100 None 1.000 35 35 1998 2017
Entrez Id: 6391
Gene Symbol: SDHC
SDHC 		Q99643 succinate dehydrogenase complex subunit C 202 0.517 0.846 2.0E-04 0.100 None 1.000 35 16 2003 2018
Entrez Id: 5892
Gene Symbol: RAD51D
RAD51D 		O75771 RAD51 paralog D 36 0.674 0.385 1.1E-09 0.100 None 1.000 31 51 1982 2018
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		Q92878 RAD50 double strand break repair protein 110 0.556 0.808 3.4E-27 0.100 None 1.000 31 164 1999 2017
Entrez Id: 580
Gene Symbol: BARD1
BARD1 		Q99728 BRCA1 associated RING domain 1 75 0.597 0.538 1.4E-24 0.100 None 1.000 28 105 2003 2017
Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13 		Q92826 homeobox B13 90 0.573 0.462 3.7E-08 0.100 None 1.000 26 1 1996 2017
Entrez Id: 641
Gene Symbol: BLM
BLM 		P54132 BLM RecQ like helicase 158 0.535 0.808 1.5E-15 0.100 None 1.000 26 10 1995 2016
Entrez Id: 2176
Gene Symbol: FANCC
FANCC 		Q00597 FA complementation group C 218 0.507 0.808 2.8E-13 0.100 None 1.000 23 6 1993 2017
Entrez Id: 4286
Gene Symbol: MITF
MITF 		O75030 melanocyte inducing transcription factor 244 0.499 0.808 0.98 0.100 None 1.000 22 1 1987 2016
Entrez Id: 4361
Gene Symbol: MRE11
MRE11 		P49959 MRE11 homolog, double strand break repair nuclease 171 0.527 0.808 1.3E-12 0.100 None 1.000 21 55 1999 2017
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1 		Q13635 patched 1 604 0.398 0.885 1.00 0.100 None 1.000 11 44 1997 2014
Entrez Id: 101927761
Gene Symbol: TH2LCRR
TH2LCRR 		T helper type 2 locus control region associated RNA 19 0.751 0.385 0.100 None 1.000 10 22 2000 2017
Entrez Id: 5424
Gene Symbol: POLD1
POLD1 		P28340 DNA polymerase delta 1, catalytic subunit 189 0.507 0.769 2.4E-06 0.100 None 1.000 7 2 2006 2017
Entrez Id: 4149
Gene Symbol: MAX
MAX 		P61244 MYC associated factor X Transcription factor 141 0.553 0.769 0.83 0.100 None 1.000 6 9 2003 2017