Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 1.000 112 3 1990 2020
Entrez Id: 176
Gene Symbol: ACAN
ACAN
P16112 aggrecan Extracellular structure 187 0.528 0.846 1.00 0.200 None 1.000 106 0 1996 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1234 0.314 0.962 1.00 0.100 None 1.000 65 1 1997 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.500 None 1.000 50 3 2000 2020
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.100 None 1.000 36 0 2012 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.100 None 1.000 35 0 2012 2020
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.100 None 1.000 35 0 2012 2020
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.100 None 1.000 35 0 2012 2020
Entrez Id: 4513
Gene Symbol: COX2
COX2
P00403 cytochrome c oxidase subunit II Enzyme 875 0.352 0.962 0.100 None 1.000 34 0 1998 2020
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
Q16552 interleukin 17A 1074 0.324 0.923 4.3E-02 0.100 None 1.000 31 1 1999 2020
Entrez Id: 107075310
Gene Symbol: MTCO2P12
MTCO2P12
MT-CO2 pseudogene 12 703 0.368 0.962 0.100 None 1.000 29 0 1998 2020
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2
Q13950 RUNX family transcription factor 2 Transcription factor 405 0.437 0.846 0.95 0.400 None 1.000 28 0 2008 2020
Entrez Id: 4803
Gene Symbol: NGF
NGF
P01138 nerve growth factor Signaling 616 0.391 0.885 0.82 0.100 None 1.000 26 0 2002 2020
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.100 None 1.000 25 0 2010 2019
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.100 None 1.000 25 0 1997 2019
Entrez Id: 406932
Gene Symbol: MIR140
MIR140
microRNA 140 144 0.522 0.769 0.100 None 1.000 24 0 2009 2020
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
P13500 C-C motif chemokine ligand 2 Signaling 1157 0.321 0.962 0.61 0.100 None 1.000 24 1 1992 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.100 None 1.000 23 0 2017 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.100 None 1.000 20 0 2017 2019
Entrez Id: 56729
Gene Symbol: RETN
RETN
Q9HD89 resistin 302 0.454 0.808 3.7E-02 0.100 None 1.000 20 1 2014 2019
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
P01033 TIMP metallopeptidase inhibitor 1 Enzyme modulator 603 0.380 0.885 0.50 0.100 None 1.000 20 0 1993 2020
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
Q16539 mitogen-activated protein kinase 14 Kinase 626 0.379 0.923 0.37 0.100 None 1.000 19 0 2007 2020
Entrez Id: 10598
Gene Symbol: AHSA1
AHSA1
O95433 activator of HSP90 ATPase activity 1 526 0.396 0.923 1.00 0.100 None 1.000 18 0 2007 2020
Entrez Id: 1398
Gene Symbol: CRK
CRK
P46108 CRK proto-oncogene, adaptor protein 544 0.394 0.923 0.96 0.100 None 1.000 18 0 2007 2020
Entrez Id: 1401
Gene Symbol: CRP
CRP
P02741 C-reactive protein 1483 0.299 0.962 3.7E-03 0.100 None 1.000 18 0 2008 2019