Source: CLINVAR ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 23 0.328 0.923 6.0E-03 0.700 None 1.000 0 1 1989 2019
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 33 0.373 0.962 1.00 0.640 None 1.000 0 12 1993 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 85 0.292 0.923 1.00 0.620 None 1.000 0 4 2005 2016
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2 		P21802 fibroblast growth factor receptor 2 Kinase 82 0.380 0.808 1.00 0.620 None 1.000 0 9 2007 2012
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH 		Q9UIF7 mutY DNA glycosylase Enzyme 16 0.521 0.769 1.3E-18 0.610 None 1.000 23 9 2002 2014
Entrez Id: 1316
Gene Symbol: KLF6
KLF6 		Q99612 Kruppel like factor 6 Nucleic acid binding 2 0.501 0.846 0.98 0.610 None 1.000 0 1 2005 2005
Entrez Id: 3659
Gene Symbol: IRF1
IRF1 		P10914 interferon regulatory factor 1 Transcription factor 2 0.468 0.769 0.99 0.600 None 0 1
Entrez Id: 843
Gene Symbol: CASP10
CASP10 		Q92851 caspase 10 Enzyme 4 0.528 0.692 4.6E-12 0.600 None 0 2
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 84 0.236 0.962 0.53 0.500 None 1.000 0 1 1991 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 66 0.320 0.923 7.9E-04 0.460 None 1.000 0 2 2000 2015
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3 		P21860 erb-b2 receptor tyrosine kinase 3 Kinase 12 0.448 0.808 1.7E-15 0.420 None 1.000 1 1 2008 2013
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 70 0.303 0.885 1.00 0.160 None 1.000 1 3 2004 2014
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 37 0.390 0.808 0.49 0.100 None 1.000 1 1 2014 2014