Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 54903
Gene Symbol: MKS1
MKS1
Q9NXB0 MKS transition zone complex subunit 1 Extracellular structure 231 0.505 0.769 3.4E-16 0.300 None 1.000 1 0 2006 2006
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.270 None 0.875 8 0 2012 2019
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
P05121 serpin family E member 1 Enzyme modulator 770 0.359 0.885 4.4E-02 0.260 None 1.000 8 0 2003 2017
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.260 None 1.000 7 0 2012 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.250 None 1.000 6 0 2012 2019
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
Q9UBK2 PPARG coactivator 1 alpha Transcription factor 350 0.453 0.885 1.00 0.240 None 1.000 5 0 2011 2019
Entrez Id: 2022
Gene Symbol: ENG
ENG
P17813 endoglin 371 0.446 0.846 1.00 0.230 None 1.000 5 0 2005 2016
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
P01579 interferon gamma 1519 0.288 0.962 0.47 0.220 None 1.000 3 0 1999 2017
Entrez Id: 114757
Gene Symbol: CYGB
CYGB
Q8WWM9 cytoglobin 88 0.579 0.577 0.10 0.220 None 1.000 3 0 2010 2018
Entrez Id: 1191
Gene Symbol: CLU
CLU
P10909 clusterin 412 0.426 0.885 7.8E-05 0.210 None 1.000 2 0 2012 2014
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 1082 0.328 0.923 1.0E-37 0.210 None 1.000 2 0 2000 2002
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
P04839 cytochrome b-245 beta chain Ion channel 343 0.452 0.885 1.00 0.210 None 1.000 1 0 2012 2012
Entrez Id: 389075
Gene Symbol: RESP18
RESP18
Q5W5W9 regulated endocrine specific protein 18 4 0.931 0.154 8.7E-10 0.200 None 1.000 1 0 2018 2018
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
P25101 endothelin receptor type A G-protein coupled receptor 427 0.426 0.885 0.99 0.200 None 1.000 1 0 2000 2000
Entrez Id: 7498
Gene Symbol: XDH
XDH
P47989 xanthine dehydrogenase Enzyme 165 0.529 0.846 2.6E-22 0.200 None 1.000 1 0 2012 2012
Entrez Id: 6778
Gene Symbol: STAT6
STAT6
P42226 signal transducer and activator of transcription 6 Nucleic acid binding 281 0.475 0.808 0.99 0.200 None 1.000 1 0 2005 2005
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
P01116 KRAS proto-oncogene, GTPase Enzyme modulator 1213 0.320 0.923 7.9E-04 0.200 None 1.000 1 0 2012 2012
Entrez Id: 1889
Gene Symbol: ECE1
ECE1
P42892 endothelin converting enzyme 1 Enzyme 157 0.541 0.769 0.96 0.200 None 1.000 1 0 2000 2000
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
O60603 toll like receptor 2 749 0.361 0.923 1.0E-06 0.200 None 1.000 1 0 2012 2012
Entrez Id: 177
Gene Symbol: AGER
AGER
Q15109 advanced glycosylation end-product specific receptor Receptor 450 0.420 0.885 6.4E-16 0.200 None 1.000 1 0 2011 2011
Entrez Id: 4688
Gene Symbol: NCF2
NCF2
P19878 neutrophil cytosolic factor 2 Enzyme 90 0.601 0.692 4.0E-07 0.200 None 1.000 1 0 2012 2012
Entrez Id: 6348
Gene Symbol: CCL3
CCL3
P10147 C-C motif chemokine ligand 3 Signaling 282 0.460 0.885 0.35 0.200 None 1.000 1 0 2011 2011
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.100 None 1.000 107 0 2004 2020
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
P84022 SMAD family member 3 Transcription factor 470 0.415 0.923 0.80 0.100 None 1.000 31 0 2011 2020
Entrez Id: 9365
Gene Symbol: KL
KL
Q9UEF7 klotho Enzyme 332 0.448 0.769 2.2E-04 0.100 None 1.000 22 0 2011 2019