Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
P35222 catenin beta 1 1368 0.303 0.885 1.00 0.500 None 1.000 22 10 2001 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.200 None 1.000 21 5 2010 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
P28482 mitogen-activated protein kinase 1 Kinase 1059 0.330 0.923 1.00 0.100 None 1.000 21 0 2010 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 2367 0.248 0.962 0.32 0.100 None 1.000 20 2 1995 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.100 None 1.000 20 0 2000 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.100 None 0.947 19 1 1999 2020
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
P03372 estrogen receptor 1 Nuclear receptor 1101 0.324 0.962 1.00 0.100 None 1.000 18 2 2006 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.100 None 1.000 18 0 2002 2019
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 653 0.376 0.885 1.00 0.100 None 1.000 17 0 2012 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.100 None 1.000 17 0 2017 2020
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
P04818 thymidylate synthetase Enzyme 406 0.425 0.846 0.72 0.400 None 0.882 17 0 2006 2018
Entrez Id: 9476
Gene Symbol: NAPSA
NAPSA
O96009 napsin A aspartic peptidase Enzyme 89 0.576 0.654 7.2E-14 0.100 None 1.000 17 0 1999 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
P42771 Q8N726 cyclin dependent kinase inhibitor 2A 1314 0.300 0.885 0.39 0.200 None 0.933 15 5 1996 2016
Entrez Id: 1287
Gene Symbol: COL4A5
COL4A5
P29400 collagen type IV alpha 5 chain 124 0.553 0.654 1.00 0.100 None 1.000 15 0 2013 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.100 None 1.000 15 0 2013 2019
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 336 0.435 0.846 0.100 None 1.000 15 1 2010 2020
Entrez Id: 3799
Gene Symbol: KIF5B
KIF5B
P33176 kinesin family member 5B Cellular structure 67 0.604 0.538 0.99 0.100 None 1.000 15 0 2009 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
P14780 matrix metallopeptidase 9 Enzyme 1337 0.305 0.923 1.9E-17 0.100 None 1.000 15 0 2007 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC
P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 821 0.344 0.923 1.00 0.500 None 1.000 15 3 2008 2018
Entrez Id: 81031
Gene Symbol: SLC2A10
SLC2A10
O95528 solute carrier family 2 member 10 Transporter 135 0.550 0.615 1.6E-08 0.100 None 1.000 15 0 2013 2019
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
P08069 insulin like growth factor 1 receptor Kinase 556 0.399 0.885 0.97 0.100 None 1.000 14 1 2006 2019
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 726 0.363 0.846 0.100 None 1.000 14 0 2009 2019
Entrez Id: 4582
Gene Symbol: MUC1
MUC1
P15941 mucin 1, cell surface associated 594 0.384 0.885 1.9E-02 0.100 None 1.000 14 1 2000 2017
Entrez Id: 8626
Gene Symbol: TP63
TP63
Q9H3D4 tumor protein p63 Transcription factor 816 0.362 0.769 1.00 0.500 None 0.929 14 7 2010 2017
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
P46937 Yes associated protein 1 Enzyme modulator 374 0.432 0.808 1.00 0.100 None 1.000 13 1 2014 2019